Alzheimer Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-10-23Clinical Trial Update: A Study of the Safety, Tolerability, and Pharmacodynamics of MK-8931 in Participants With Alzheimer's Disease (MK-8931-010 AM1 [P07820 AM1]) [Phase 1]
This completed Phase 1 study evaluated the safety, tolerability, and pharmacodynamics of verubecestat (MK-8931) in participants with Alzheim…
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CLINICAL_TRIALS trial_result · 2015-10-19Clinical Trial Update: Safety and Effectiveness Study of Intranasal Insulin Glulisine on Cognitive and Memory in Mild-Mod AD Patients. [Phase 2]
Phase 2 clinical trial update evaluating the safety and cognitive/memory effects of intranasal insulin glulisine in patients with mild-to-mo…
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CLINICAL_TRIALS trial_result · 2015-10-12Clinical Trial Update: A Phase II, Multicenter, Double Blind, Placebo-Controlled Safety, Tolerability Study of BMS-708163 in Patients With Mild to Moderate Alzheimer's Disease [Phase 2]
Phase II randomized, double-blind, placebo-controlled study assessing the safety and tolerability of BMS-708163 in patients with mild to mod…
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CLINICAL_TRIALS trial_result · 2015-10-12Clinical Trial Update: Safety Study of AADvac1, a Tau Peptide-KLH-Conjugate Active Vaccine to Treat Alzheimer's Disease [Phase 1]
A Phase 1 safety study of AADvac1, a tau peptide-KLH-conjugate active vaccine, for Alzheimer's disease has completed.
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CLINICAL_TRIALS trial_result · 2015-10-12Clinical Trial Update: A Multicenter, Double Blind, Placebo-Controlled, Safety and Tolerability Study of BMS-708163 in Patients With Prodromal Alzheimer's Disease [Phase 2]
Phase 2 multicenter, double-blind, placebo-controlled safety and tolerability study of BMS-708163 in prodromal Alzheimer's disease was termi…
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CLINICAL_TRIALS trial_result · 2015-10-05Clinical Trial Update: Cognitive and Neurophysiological Effects of Raloxifene in Alzheimer's Disease [Phase 2, Phase 3]
A completed Phase 2/3 clinical trial evaluated the cognitive and neurophysiological effects of raloxifene in Alzheimer's disease.
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CLINICAL_TRIALS trial_result · 2015-09-30Clinical Trial Update: Yoga for Family Caregivers of Alzheimers Disease Patient [NA]
A completed clinical trial from the Federal University of São Paulo evaluated yoga for reducing stress and anxiety among family caregivers o…
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CLINICAL_TRIALS trial_result · 2015-09-28Clinical Trial Update: Safety and Efficacy of MT-4666 [Phase 2]
Phase 2 clinical trial evaluating the safety and efficacy of MT-4666 for Alzheimer's disease has completed.
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CLINICAL_TRIALS trial_result · 2015-09-28Clinical Trial Update: Evaluation of Reader Training Processes [Phase 4]
Phase 4 study by Avid Radiopharmaceuticals evaluating reader training processes for Alzheimer's disease imaging completed; results posted in…
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CLINICAL_TRIALS trial_result · 2015-08-19Clinical Trial Update: Specific Care and Assistance Plan for Alzheimer's Disease [NA]
Completed clinical trial evaluating a Specific Care and Assistance Plan for Alzheimer's disease conducted by University Hospital, Toulouse.
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CLINICAL_TRIALS trial_result · 2015-08-14Clinical Trial Update: Physical Training and Cognitive Activity on the Mild Cognitive Impairment (MCI) Patient [NA]
The clinical trial evaluating physical training and cognitive activity in patients with Mild Cognitive Impairment and Alzheimer's disease ha…
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CLINICAL_TRIALS trial_result · 2015-08-13Clinical Trial Update: A Study to Evaluate the Effect of Bexarotene on Beta-Amyloid and Apolipoprotein E Metabolism in Healthy Subjects [Phase 1]
A completed Phase 1 study evaluated the effect of bexarotene on beta-amyloid and apolipoprotein E metabolism in healthy subjects.
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CLINICAL_TRIALS trial_result · 2015-08-11Clinical Trial Update: A Study to Assess Regional Cerebral Blood Flow as an Alzheimer's Disease Biomarker Compared to Positron Emission Tomography in Patients With Mild-to-Moderate Alzheimer's Disease and Cognitively Normal Elderly Subjects (Study MK-0000-068)(COMPLETED) [Phase 1]
This completed Phase 1 study evaluated regional cerebral blood flow as a biomarker for Alzheimer's disease. It compared this biomarker to PE…
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CLINICAL_TRIALS trial_result · 2015-08-04Clinical Trial Update: Markers of Alzheimers Disease After Propofol or Isoflurane Anesthesia [Phase 1]
Phase 1 clinical trial evaluating whether anesthesia with propofol or isoflurane influences biomarkers associated with Alzheimer's disease; …
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CLINICAL_TRIALS trial_result · 2015-07-24Clinical Trial Update: Study of MK0677 for the Treatment of Alzheimer's Disease (0677-030)(COMPLETED) [Phase 2]
A Phase 2 trial of MK0677 for Alzheimer's disease has completed.
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CLINICAL_TRIALS trial_result · 2015-07-23Clinical Trial Update: A Study to Evaluate the Use of an Indwelling Catheter to Obtain Cerebrospinal Fluid (CSF) by Low-rate Continuous Sampling (MK-0000-211)
This update reports the completion of a clinical trial evaluating a low-rate, continuous sampling indwelling catheter to obtain cerebrospina…
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CLINICAL_TRIALS trial_result · 2015-07-14Clinical Trial Update: Memory and Insulin in Early Alzheimer's Disease [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating memory and insulin approaches in early Alzheimer's disease. The study is completed, with results posted …
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CLINICAL_TRIALS trial_result · 2015-07-09Clinical Trial Update: The Feasibility of Florbetapir Quantitation in Europe [Phase 4]
Phase 4 study evaluating the feasibility of quantifying florbetapir in Europe for Alzheimer's disease; results were posted in 2015.
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CLINICAL_TRIALS trial_result · 2015-06-25Clinical Trial Update: A Study to Evaluate the Effects of JNJ-54861911 on Amyloid Beta Processing in Cerebrospinal Fluid and Plasma in Patients With Prodromal Alzheimer's Disease [Phase 1]
Phase 1 study evaluating JNJ-54861911 on amyloid-beta processing in cerebrospinal fluid and plasma in prodromal Alzheimer's disease has comp…
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CLINICAL_TRIALS trial_result · 2015-06-24Clinical Trial Update: Escitalopram Treatment for BPSD in Alzheimer's Disease in Comparison to Risperidone [Phase 4]
A Phase 4 trial comparing escitalopram to risperidone for behavioral and psychological symptoms in Alzheimer's disease has completed.
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CLINICAL_TRIALS trial_result · 2015-06-24Clinical Trial Update: Follow-up Study to Assess Safety and Clinical Activity of Continued AFFITOPE® AD02 Vaccinations of Patients Who Participated in AFF006 [Phase 2]
A Phase 2 follow-up study evaluating continued AFFITOPE AD02 vaccinations in Alzheimer's disease participants has been terminated.
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CLINICAL_TRIALS trial_result · 2015-06-17Clinical Trial Update: CATIE-Alzheimer's Disease Trial [NA]
This entry notes that the CATIE-AD Alzheimer's trial sponsored by the National Institute of Mental Health has completed.
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: A Randomized, Double-blind, Placebo-controlled Study to Assess Safety, Tolerability, Pharmacokinetics, Immunogenicity, and Pharmacodynamic Response of Repeated Intravenous Infusions of BAN2401 in Subjects With Mild Cognitive Impairment Due to Alzheimer's Disease and Mild Alzheimer's Disease [Phase 1]
This Phase 1 randomized, double-blind, placebo-controlled study evaluated safety, tolerability, pharmacokinetics, immunogenicity, and pharma…
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CLINICAL_TRIALS trial_result · 2015-06-08Clinical Trial Update: A Study to Evaluate the Effects of MK-0249 and an Alzheimer's Disease Medication on Cognitive Function in Adults With Alzheimer's Disease (MK-0249-023) [Phase 1]
A Phase 1 trial evaluating MK-0249 with an Alzheimer's disease medication in adults with Alzheimer’s disease and dementia was terminated; re…
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CLINICAL_TRIALS trial_result · 2015-06-03Clinical Trial Update: Efficacy, Safety, & Tolerability of AZD3480 Patients With Mild to Moderate Dementia of the Alzheimer's Type (AD) [Phase 2]
A Phase 2 study of AZD3480 in mild to moderate Alzheimer's disease has completed. The trial evaluated efficacy, safety, and tolerability.