Alzheimer Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-07-20Clinical Trial Update: Multi-centre Study of HTL0018318 in Patients as an add-on to Standard-of-care [Phase 1]
This update reports the completion of a multi-centre Phase 1 trial evaluating HTL0018318 as an add-on to standard of care in Alzheimer's dis…
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CLINICAL_TRIALS trial_result · 2018-07-06Clinical Trial Update: A Study Assessing Bryostatin in the Treatment of Moderately Severe to Severe Alzheimer's Disease [Phase 2]
Phase 2 study evaluating Bryostatin for moderately to severely Alzheimer's disease has completed, with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-05Clinical Trial Update: Screening and Evaluation of Patients With Signs and Symptoms of Alzheimer's Disease
This clinical trial update reports completion of a study evaluating screening and evaluation methods for patients with signs and symptoms of…
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CLINICAL_TRIALS trial_result · 2018-06-14Clinical Trial Update: Clinical Evaluation of Florbetapir F 18 (18F-AV-45) [Phase 2]
Phase 2 clinical evaluation of Florbetapir F-18 (18F-AV-45) completed; results posted.
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CLINICAL_TRIALS trial_result · 2018-06-14Clinical Trial Update: Blood-Brain-Barrier Opening Using Focused Ultrasound With IV Contrast Agents in Patients With Early Alzheimer's Disease [NA]
A completed clinical trial assessed whether focused ultrasound with intravenous contrast agents can open the blood-brain barrier in patients…
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CLINICAL_TRIALS trial_result · 2018-06-12Clinical Trial Update: Good Rate of Clinical Response to Cholinesterase Inhibitors in Alzheimer's Disease After Three Months of Treatment
A clinical trial update reports a favorable rate of clinical response to cholinesterase inhibitors in Alzheimer's disease after three months…
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CLINICAL_TRIALS trial_result · 2018-06-06Clinical Trial Update: Efficacy and Safety Study of ABT-288 in Subjects With Mild-to-Moderate Alzheimer's Disease [Phase 2]
Phase 2 efficacy and safety study of ABT-288 in mild-to-moderate Alzheimer's disease has completed.
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CLINICAL_TRIALS trial_result · 2018-06-01Clinical Trial Update: Efficacy of Circadin® 2 mg in Patients With Mild to Moderate Alzheimer Disease Treated With AChE Inhibitor [Phase 2]
Phase 2 trial evaluating Circadin 2 mg in patients with mild-to-moderate Alzheimer's disease who are on acetylcholinesterase inhibitors. The…
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CLINICAL_TRIALS trial_result · 2018-05-29Clinical Trial Update: Alzheimer's Disease and Physiological, Cognitive Function and BDNF Levels of Plasma Adaptation After Exercise Training [NA]
A completed clinical trial in Alzheimer's disease assessing the effects of exercise training on physiological and cognitive function and pla…
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CLINICAL_TRIALS trial_result · 2018-05-18Clinical Trial Update: Study of LY2886721 in Mild Cognitive Impairment Due to Alzheimer's Disease or Mild Alzheimer's Disease [Phase 1, Phase 2]
A Phase 1/Phase 2 study of LY2886721 for mild cognitive impairment due to Alzheimer's disease or mild Alzheimer's disease was terminated; re…
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CLINICAL_TRIALS trial_result · 2018-05-16Clinical Trial Update: An Efficacy and Safety Trial of Verubecestat (MK-8931) in Mild to Moderate Alzheimer's Disease (P07738) [Phase 2, Phase 3]
Clinical trial update for verubecestat (MK-8931) in mild to moderate Alzheimer's disease showing termination with posted results in 2018.
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CLINICAL_TRIALS trial_result · 2018-05-03Clinical Trial Update: Continued Safety Monitoring of Solanezumab (LY2062430) in Alzheimer's Disease [Phase 3]
Continued safety monitoring update for solanezumab (LY2062430) in Alzheimer's disease under a Phase 3 study; the trial is terminated with re…
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CLINICAL_TRIALS trial_result · 2018-04-30Clinical Trial Update: Safety Follow-up Study for Subjects With Agitation Associated With Dementia of the Alzheimer's Type Who Previously Participated in a Double-blind Trial of Brexpiprazole or Placebo
Reports the completion of a safety follow-up study of brexpiprazole (Rexulti) versus placebo in subjects with agitation associated with Alzh…
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CLINICAL_TRIALS trial_result · 2018-04-27Clinical Trial Update: Open Label Study of TRx0014 in Alzheimer's Disease [Phase 2]
Open-label Phase 2 trial of TRx0014 in Alzheimer's disease has completed. No efficacy data are provided in the snippet.
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CLINICAL_TRIALS trial_result · 2018-04-17Clinical Trial Update: Skeletal Muscle as a Mediator of Exercise Induced Effects on Metabolism & Cognitive Function: Role for Myokines & miRNAs [NA]
A completed clinical trial from the Slovak Academy of Sciences examined how skeletal muscle signals mediate exercise-related metabolic and c…
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: Early Markers of Cognitive Change and Alzheimer s Disease
A completed clinical trial update from the National Institute on Aging reports findings on early markers of cognitive change related to Alzh…
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CLINICAL_TRIALS trial_result · 2018-04-05Clinical Trial Update: In Vivo Imaging of Therapeutic Electric Current Flow
Clinical trial update noting the completed study on in vivo imaging of therapeutic electric current flow, with listed conditions including P…
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CLINICAL_TRIALS trial_result · 2018-04-04Clinical Trial Update: Positron Emission Tomography (PET) Study in Patients With Alzheimer's Disease [Phase 1]
A Phase 1 positron emission tomography study in Alzheimer's disease sponsored by H. Lundbeck A/S has been terminated.
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CLINICAL_TRIALS trial_result · 2018-04-03Clinical Trial Update: Clinical Pharmacology of p38 MAP Kinase Inhibitor, VX-745, in Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD [Phase 2]
A Phase 2 clinical trial update reports pharmacology results for VX-745, a p38 MAP kinase inhibitor, studied in mild cognitive impairment du…
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CLINICAL_TRIALS trial_result · 2018-04-03Clinical Trial Update: P75NTR, Diagnostic Biomarker for Alzheimer's Disease: Quantification Study in Cerebrospinal Fluid
A completed clinical trial from University Hospital, Toulouse evaluated the p75NTR biomarker quantification in cerebrospinal fluid for Alzhe…
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CLINICAL_TRIALS trial_result · 2018-03-20Clinical Trial Update: A Repeated Dose Study of KHK6640 in Japanese Patients With Alzheimer's Disease [Phase 1]
This clinical trial update reports the completion of a Phase 1 repeated-dose study of KHK6640 in Japanese patients with Alzheimer's disease.
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CLINICAL_TRIALS trial_result · 2018-03-19Clinical Trial Update: Effects of Doxycycline and Rifampicin on Biomarkers of Alzheimer's Disease in the Cerebrospinal Fluid [Phase 3]
A completed Phase 3 clinical trial evaluating whether doxycycline plus rifampicin affects biomarkers in the cerebrospinal fluid of people wi…
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CLINICAL_TRIALS trial_result · 2018-03-14Clinical Trial Update: Safety and Efficacy Study Evaluating TRx0237 in Subjects With Mild to Moderate Alzheimer's Disease [Phase 3]
A Phase 3 safety and efficacy trial of TRx0237 in subjects with mild to moderate Alzheimer's disease has completed.
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CLINICAL_TRIALS trial_result · 2018-03-14Clinical Trial Update: Progress of Mild Alzheimer's Disease in Participants on Solanezumab Versus Placebo [Phase 3]
Phase 3 trial update comparing mild Alzheimer's disease progression in participants on solanezumab vs placebo; study terminated with results…
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CLINICAL_TRIALS trial_result · 2018-03-14Clinical Trial Update: Safety and Efficacy Study Evaluating TRx0237 in Subjects With Mild Alzheimer's Disease [Phase 3]
This document provides an update on a Phase 3 safety and efficacy trial evaluating TRx0237 in subjects with mild Alzheimer's disease, which …