Alzheimer Disease

CLINICAL_TRIALS trial_result · 2025-05-14

Clinical Trial Update: Lactate for Energy and Neurocognition

A clinical trial sponsored by the University of Kansas Medical Center evaluating lactate for energy and neurocognition has completed.

CLINICAL_TRIALS trial_result · 2025-05-13

Clinical Trial Update: Novel Diagnostic and Disease Stage Biomarkers in AD

The update indicates the completed trial from the Danish Dementia Research Centre evaluating novel diagnostic and disease-stage biomarkers f…

CLINICAL_TRIALS trial_result · 2025-05-11

Clinical Trial Update: Neuronavigation-guided FUS-induced BBB Opening in Alzheimer's Disease Patients and Its Effects on Brain Amyloid and Tau [Phase 1]

Phase 1 study examining neuronavigation-guided focused ultrasound–induced opening of the blood-brain barrier in early-onset Alzheimer's dise…

CLINICAL_TRIALS trial_result · 2025-05-11

Clinical Trial Update: Safety and Pharmacokinetics of Single Ascending Doses and Multiple Ascending Doses of CS6253 in Healthy Volunteers [EARLY_Phase 1]

This early Phase 1 trial evaluated the safety and pharmacokinetics of single ascending doses and multiple ascending doses of CS6253 in healt…

CLINICAL_TRIALS trial_result · 2025-05-11

Clinical Trial Update: Using Neuroimaging to Early Diagnose Alzheimer's Disease Through Hippocampal Atrophy Assessment

A completed clinical trial evaluated the use of neuroimaging to detect hippocampal atrophy for early diagnosis of Alzheimer's disease.

CLINICAL_TRIALS trial_result · 2025-05-09

Clinical Trial Update: Trial of Dronabinol Adjunctive Treatment of Agitation in Alzheimer's Disease [Phase 2]

Phase 2 trial evaluating dronabinol as an adjunctive treatment for agitation in Alzheimer's disease has completed and posted results.

CLINICAL_TRIALS trial_result · 2025-05-08

Clinical Trial Update: Imaging Tau in Alzheimer's Disease and Normal Aging [Phase 2]

Phase 2 trial evaluating tau imaging in Alzheimer's disease and normal aging; results have been posted.

CLINICAL_TRIALS trial_result · 2025-05-06

Clinical Trial Update: Study of the Efficacy and Safety of Various Anti-inflammatory Agents in Participants With Mild Cognitive Impairment or Mild Alzheimer's Disease [Phase 2]

A Phase 2 study evaluating various anti-inflammatory agents for mild cognitive impairment or Alzheimer's disease was terminated, and results…

CLINICAL_TRIALS trial_result · 2025-05-06

Clinical Trial Update: Learning and Improving Alzheimer's Patient-Caregiver Relationships Via Smart Healthcare Technology [NA]

A clinical trial evaluating smart healthcare technology to improve Alzheimer's patient–caregiver relationships has completed, and its result…

CLINICAL_TRIALS trial_result · 2025-05-06

Clinical Trial Update: Telmisartan vs. Perindopril in Mild-Moderate Alzheimer's Disease Patients [Phase 2]

A Phase 2, head-to-head trial comparing telmisartan and perindopril in patients with mild-to-moderate Alzheimer's disease has been terminate…

CLINICAL_TRIALS trial_result · 2025-05-02

Clinical Trial Update: A Multiple Dose Trial of Emraclidine in Elderly Participants and in Participants With Dementia Due to Alzheimer's Disease [Phase 1]

Phase 1 multiple-dose trial of Emraclidine in elderly participants and in participants with Alzheimer's disease dementia has completed.

CLINICAL_TRIALS trial_result · 2025-05-02

Clinical Trial Update: Medication Repurposing to Stop Cognitive Decline in Dementia

Karolinska Institutet-led trial on repurposing a medication to halt cognitive decline in Alzheimer's disease and other forms of dementia has…

CLINICAL_TRIALS trial_result · 2025-05-02

Clinical Trial Update: Statins, Cholesterol and Cognitive Decline in Alzheimer's

This study, completed, evaluated the relationship between statin use and cholesterol levels with cognitive decline in Alzheimer's disease. T…

CLINICAL_TRIALS trial_result · 2025-05-02

Clinical Trial Update: Caregiver Outcomes of Alzheimer's Disease Screening [NA]

This clinical trial update reports the completion of a study examining caregiver outcomes after screening for Alzheimer disease. The results…

CLINICAL_TRIALS trial_result · 2025-04-30

Clinical Trial Update: Effect of Physiologic Insulin Administration on Cognition [NA]

The update reports results from a trial evaluating physiologic insulin administration and its effects on cognition in Alzheimer disease.

CLINICAL_TRIALS trial_result · 2025-04-30

Clinical Trial Update: Early-onset Alzheimer's Disease Phenotypes: Neuropsychology and Neural Networks

Completed clinical trial from UCLA investigating early-onset Alzheimer's disease phenotypes with a focus on neuropsychology and neural netwo…

CLINICAL_TRIALS trial_result · 2025-04-29

Clinical Trial Update: A Dose-ranging Study to Investigate Efficacy of Buntanetap in Mild to Moderate AD [Phase 2, Phase 3]

A dose-ranging study evaluating the efficacy of Buntanetap in mild-to-moderate Alzheimer's disease (Phase 2/3) has completed with results po…

CLINICAL_TRIALS trial_result · 2025-04-29

Clinical Trial Update: A Safety and Tolerability Study of JNJ-54861911 in Participants With Early Alzheimer's Disease [Phase 2]

A Phase 2 safety and tolerability study of the investigational compound JNJ-54861911 in participants with early Alzheimer’s disease has comp…

CLINICAL_TRIALS trial_result · 2025-04-29

Clinical Trial Update: All About Me: An Intervention to Ease the Transition to Long Term Care [NA]

This trial update notes the completed status of Hopeful Aging's 'All About Me' intervention to ease the transition to long-term care for peo…

CLINICAL_TRIALS trial_result · 2025-04-29

Clinical Trial Update: Epigenetic Biomarkers for Alzheimer's Disease

Clinical trial update from the Chinese University of Hong Kong reporting on epigenetic biomarkers in Alzheimer's disease with the study stat…