Alzheimer Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-06-13Clinical Trial Update: A Follow-On Study of Donanemab (LY3002813) With Video Assessments in Participants With Alzheimer's Disease (TRAILBLAZER-EXT) [Phase 2]
Phase 2 follow-on trial TRAILBLAZER-EXT evaluating donanemab (LY3002813) with video assessments in Alzheimer's disease has completed and pos…
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CLINICAL_TRIALS trial_result · 2025-06-12Clinical Trial Update: Exercise Workshop, Skill-Based Art Approaches, and Awareness Studies for Elderly Individuals [NA]
A completed clinical trial evaluating an exercise workshop, skill-based art approaches, and awareness activities for older adults with mild …
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CLINICAL_TRIALS trial_result · 2025-06-10Clinical Trial Update: A Study to Assess Safety and Target Engagement of E2814 in Participants With Mild to Moderate Cognitive Impairment Due to Dominantly Inherited Alzheimer's Disease [Phase 1, Phase 2]
A Phase 1/2 trial evaluating Eisai's investigational anti-tau agent E2814 for safety and target engagement in individuals with mild to moder…
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CLINICAL_TRIALS trial_result · 2025-06-10Clinical Trial Update: 18F-AV-1451 High Resolution Autopsy Study [Phase 1]
Phase 1 autopsy study update for the Alzheimer's disease imaging agent 18F-AV-1451 (flortaucipir) by Avid Radiopharmaceuticals; results have…
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CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: A Dyadic Approach for a Remote Physical Activity Intervention in Adults With AD and Their Caregivers [NA]
This clinical trial evaluated a remote, dyadic physical activity intervention for adults with Alzheimer's disease and their caregivers. The …
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CLINICAL_TRIALS trial_result · 2025-06-08Clinical Trial Update: Aβ Dynamics in LLMD [Phase 4]
A Phase 4 clinical trial evaluating beta-amyloid dynamics in late-life major depressive disorder and Alzheimer's disease is currently recrui…
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CLINICAL_TRIALS trial_result · 2025-06-06Clinical Trial Update: Imaging of Brain Amyloid Plaques in the Aging Population [Phase 4]
Phase 4 clinical trial update noting ongoing enrollment (enrolling by invitation) to image brain amyloid plaques in aging populations, inclu…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: Effect of Exercise, Endocannabinoids and Ketones on Cerebral Metabolism in a Cognitive Disorders Population [NA]
A completed clinical trial studied the effects of exercise, endocannabinoids, and ketones on cerebral metabolism in individuals with cogniti…
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: BRain Energy Activation With Ketones to Prevent Alzheimer's Disease [NA]
A completed clinical trial assessing brain energy activation with ketones to prevent Alzheimer's disease in individuals with mild cognitive …
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CLINICAL_TRIALS trial_result · 2025-06-03Clinical Trial Update: Rocky Mountain Alzheimer's Disease Center Longitudinal Biomarker and Clinical Phenotyping Study
This ClinicalTrials.gov update reports termination of the Rocky Mountain Alzheimer's Disease Center Longitudinal Biomarker and Clinical Phen…
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CLINICAL_TRIALS trial_result · 2025-05-30Clinical Trial Update: Assessment of the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type [Phase 3]
Phase 3 trial evaluating AVP-786 for agitation in Alzheimer's disease dementia has been terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2025-05-30Clinical Trial Update: Study to Assess the Efficacy, Safety, and Tolerability of AVP-786 for the Treatment of Agitation in Patients With Dementia of the Alzheimer's Type [Phase 3]
Phase 3 trial of AVP-786 for agitation in Alzheimer's-type dementia was terminated; results have been posted (2025-05-30).
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CLINICAL_TRIALS trial_result · 2025-05-25Clinical Trial Update: Use of a Cannabinoids as a Treatment Strategy for Alzheimer's Disease [Phase 2]
Phase 2 clinical trial evaluating cannabinoids as a treatment strategy for Alzheimer's disease has been completed, with results reported.
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CLINICAL_TRIALS trial_result · 2025-05-25Clinical Trial Update: Simufilam 100 mg for Mild-to-Moderate Alzheimer's Disease [Phase 3]
The Phase 3 trial of simufilam 100 mg for mild-to-moderate Alzheimer's disease has completed, with results posted on 2025-05-25.
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CLINICAL_TRIALS trial_result · 2025-05-25Clinical Trial Update: Ultrasonic Neuromodulation for Treatment of Cognitive Impairment [Phase 1, Phase 2]
A University of Utah-sponsored clinical trial evaluated ultrasonic neuromodulation for cognitive impairment, including Alzheimer's disease a…
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CLINICAL_TRIALS trial_result · 2025-05-22Clinical Trial Update: Transcranial Electromagnetic Treatment Against Alzheimer's Disease [NA]
Clinical trial evaluating a transcranial electromagnetic treatment for Alzheimer disease has completed, sponsored by NeuroEM Therapeutics, I…
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CLINICAL_TRIALS trial_result · 2025-05-22Clinical Trial Update: MASC: Reducing Stress for Caregivers [NA]
The MASC study (Reducing Stress for Caregivers) completed and posted results, sponsored by Massachusetts General Hospital, investigating car…
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CLINICAL_TRIALS trial_result · 2025-05-22Clinical Trial Update: Patient-Centered Dementia Care Practice Coaching Intervention [NA]
A completed clinical trial evaluating a patient-centered dementia care practice coaching intervention; no pharmacologic therapy is involved.
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CLINICAL_TRIALS trial_result · 2025-05-21Clinical Trial Update: Co-design and Pilot Study in VR-based Physical Activity and Cognitive Training [NA]
A completed pilot study evaluating a virtual reality program for physical activity and cognitive training in individuals with dementia and A…
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CLINICAL_TRIALS trial_result · 2025-05-18Clinical Trial Update: Evaluation of Imaging Characteristics of [18F]PI-2620 PET in AD and PSP Patients Using High and Low Specific Activity [Phase 1]
A completed Phase 1 trial evaluating the imaging characteristics of the PET tracer [18F]PI-2620 in Alzheimer's disease and progressive supra…
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CLINICAL_TRIALS trial_result · 2025-05-15Clinical Trial Update: The PREVENTION Trial: Precision Recommendations to Optimize Neurocognition [NA]
Update on the PREVENTION trial focusing on precision recommendations to optimize neurocognition in Alzheimer’s disease and mild cognitive im…
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CLINICAL_TRIALS trial_result · 2025-05-15Clinical Trial Update: TMS as a Treatment for Apathy in Alzheimer's Disease [NA]
A Massachusetts General Hospital trial evaluating transcranial magnetic stimulation for apathy in Alzheimer's disease has been terminated.
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: Multiple Ascending Dose Safety, Tolerability, PK Study of AL001 in Alzheimer's Disease Patients & Healthy Adult Subjects [Phase 1, Phase 2]
Alzamend Neuro completed a multiple ascending dose study evaluating safety, tolerability, and pharmacokinetics of AL001 in Alzheimer's disea…
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: Open-label Extension for Phase 3 Clinical Trials of Simufilam [Phase 3]
Open-label extension updates for Phase 3 trials of Simufilam in Alzheimer's disease have been reported. The trials were terminated and resul…
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CLINICAL_TRIALS trial_result · 2025-05-14Clinical Trial Update: Learning and Coping With Early Stage Dementia [NA]
The clinical trial studying learning and coping with early-stage dementia has completed.