Alzheimer Disease
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7812653 in Participants With Early Symptomatic Alzheimer's Disease (eAD) [Phase 1]
A Phase 1 clinical trial is evaluating the safety, tolerability, pharmacokinetics, and pharmacodynamics of RO7812653 in adults with early sy…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Effects of Electrical Stimulation on Verbal Learning in Typical and Atypical Alzheimer's Disease [NA]
This clinical trial update from Johns Hopkins reports on evaluating electrical stimulation to improve verbal learning in adults with Alzheim…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4) [Phase 3]
A Phase 3 ADEPT-4 study evaluating KarXT for psychosis associated with Alzheimer's disease is currently recruiting. Sponsor Karuna Therapeut…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Efficacy of Lecanemab at Different Therapeutic Doses for Alzheimer's Disease (AD) in Real-World Practice
A clinical trial registry entry outlines evaluating lecanemab at various doses for Alzheimer's disease in real-world practice; the study sta…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Senolytic Therapy to Modulate the Progression of Alzheimer's Disease (SToMP-AD) Study [Phase 2]
A Phase 2 clinical trial update for the SToMP-AD Alzheimer's disease study indicates the senolytic therapy is currently active but not recru…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: The Care for America's Aging Study [NA]
This clinical trial update reports on the Care for America's Aging Study led by Massachusetts General Hospital, focusing on cognitive impair…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2) [Phase 3]
This document reports a Phase 3 clinical trial update for KarXT plus KarX-EC in cognitive impairment associated with Alzheimer's disease, cu…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Assessment of Sleep Disturbance in Alzheimer Disease [NA]
This update reports the completed status of a clinical trial evaluating sleep disturbances in Alzheimer disease.
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: Comparison of the Effectiveness of Treadmill-Based Walking and Dual-Task Walking Training in Alzheimer's Disease [NA]
This clinical trial update notes ongoing recruitment for a study comparing treadmill-based walking to dual-task walking training in Alzheime…
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CLINICAL_TRIALS research · 2026-03-31Clinical Trial Update: The Volunteering-in-Place Program for Apathetic Assisted Living Residents With ADRD [NA]
Clinical trial update for a volunteering-in-place program addressing apathy in residents with dementia, with the study currently NOT_RECRUIT…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Multi-modal Large Language Model-Empowered Talk Therapy for Older Adults With ADRD [NA]
Clinical trial update for a study evaluating multimodal, large language model-empowered talk therapy for older adults with mild cognitive im…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: MIMA Pilot Study: MIcrostructure of the Medial Temporal Lobe in Early Alzheimer's Disease [NA]
A recruiting clinical trial called the MIMA Pilot Study investigating microstructure of the medial temporal lobe in early Alzheimer disease.
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Sleep Aging and Risk for Alzheimer's 2.0
An active-not-recruiting NYU Langone Health study examines how sleep aging relates to Alzheimer's disease risk, exploring the link between A…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Safety and Efficacy of L. Lactis CKDB001 in Subjects With Early Alzheimer's Disease [NA]
This clinical trial is evaluating the safety and efficacy of the probiotic Lactococcus lactis CKDB001 in individuals with early Alzheimer's …
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Connect-Home: Alzheimer's Disease and Related Dementias [NA]
Connect-Home is a clinical trial studying Alzheimer's disease and related dementias led by the University of North Carolina, Chapel Hill. Th…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Chronic Treatment of Alzheimer's Disease by Gamma Light and Sound Therapy [NA]
Clinical trial registry entry indicates ongoing research on chronic gamma light and sound therapy for Alzheimer's disease. The study is curr…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Cannabidiol Solution for the Treatment of Behavioral Symptoms in Older Adults With Mild Cognitive Impairment or Alzheimer's Dementia [EARLY_Phase 1]
Clinical trial update for an early-phase study evaluating a cannabidiol solution to treat behavioral symptoms in older adults with mild cogn…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: The Comparative Effectiveness Dementia & Alzheimer's Registry
This clinical trial update reports enrollment activity for the Comparative Effectiveness Dementia & Alzheimer's Registry sponsored by Weill …
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5) [Phase 3]
This is a Phase 3 clinical trial update for donanemab in early symptomatic Alzheimer's disease (TRAILBLAZER-ALZ 5), currently recruiting.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Wake Forest Alzheimer's Disease Clinical Core
Wake Forest's Alzheimer's Disease Clinical Core is currently recruiting for a study involving Alzheimer's disease and mild cognitive impairm…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Brain Effects of Gamma Frequency Sensory Stimulation (40Hz Light, Sound and Other Devices) [Phase 2]
Phase 2 clinical trial evaluating gamma-frequency sensory stimulation (40 Hz light, sound, and related devices) for brain effects in cogniti…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Study of LY4006895 in Healthy Participants With Early Symptomatic Alzheimer's Disease (AD) [Phase 1]
A Phase 1 clinical trial evaluating LY4006895 in healthy participants with early symptomatic Alzheimer's disease; recruitment is ongoing.
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Inspiring Seniors Towards Exercise Promotion to Protect Cognition [NA]
A clinical trial sponsored by Emory University is recruiting to evaluate whether a program promoting exercise can protect cognition in older…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Early-Stage Partner in Care Living Alone Plus [NA]
Clinical trial update for an early-stage partner in care program (Living Alone Plus) targeting dementia and mild cognitive impairment; the s…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Primary Care Detection of Cognitive Impairment Leveraging Health & Consumer Technologies in Underserved Communities: The MyCog Trial [NA]
The MyCog trial is currently recruiting to test primary care detection of cognitive impairment in underserved communities using health and c…