Alzheimer Disease

• CLINICAL_TRIALS research · 2025-03-19
  Clinical Trial Update: A Study of CM383 in Patients With Alzheimer's Disease Related Mild Cognitive Impairment and Mild Alzheimer's Disease [Phase 1]

  A Phase 1 clinical trial (NCT06619613) evaluating CM383 in patients with Alzheimer's-related mild cognitive impairment and mild Alzheimer's …

• CLINICAL_TRIALS research · 2025-03-18
  Clinical Trial Update: Discovery and Validation of Protein Structural Complexes in Circulating Biofluids As Novel Biomarkers for Early Diagnosis, Prognosis and Therapeutic Management of Patients Affected by Neurodegenerative Disorders

  This clinical trial seeks to discover and validate protein structural complexes in circulating biofluids as biomarkers for early diagnosis, …

• CLINICAL_TRIALS research · 2025-03-17
  Clinical Trial Update: Reducing African American's Alzheimer's Risk Through Exercise-Mild Cognitive Impairment (RAATE-MCI) [NA]

  A Pennington Biomedical Research Center-led clinical trial aims to reduce Alzheimer's risk in individuals with mild cognitive impairment thr…

• CLINICAL_TRIALS research · 2025-03-17
  Clinical Trial Update: Brain Connectivity Marker for Alzheimer's Disease

  A Karolinska Institutet-led study investigating a brain connectivity biomarker for Alzheimer's disease is currently recruiting. The Clinical…

• CLINICAL_TRIALS research · 2025-03-13
  Clinical Trial Update: An Innovative Method in SAliva Samples for the Early Differential Diagnosis of High-impact NeuroDegenerative Diseases Through Raman Spectroscopy

  This clinical trial update describes a saliva-based Raman spectroscopy method to differentiate among several high-impact neurodegenerative d…

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• CLINICAL_TRIALS research · 2025-03-13
  Clinical Trial Update: Cardiac-Control Affecting Learning Through Mindfulness (CALM) [NA]

  An ongoing clinical trial called CALM is investigating cardiac-control affecting learning through mindfulness in older adults with age-relat…

• CLINICAL_TRIALS research · 2025-03-11
  Clinical Trial Update: An Exploratory Study to Confirm Efficacy of Modified Deep Cervical Lymphovenous Anastomosis (LVA) in Alzheimer's Disease/ Parkinson's Disease [NA]

  This clinical trial update indicates recruitment is ongoing for an exploratory study to assess the efficacy of modified deep cervical lympho…

• CLINICAL_TRIALS research · 2025-03-10
  Clinical Trial Update: Efficacy and Safety of Conventional Symptomatic Drugs Combined with Lencanizumab in the Treatment of Early Alzheimer's Disease: a Multicenter, Prospective, Observational Study

  A multicenter, prospective observational study evaluating the safety and efficacy of combining conventional symptomatic Alzheimer's therapie…

• CLINICAL_TRIALS research · 2025-03-04
  Clinical Trial Update: Educational Support Group Program for Bilingual and Spanish-speaking Carepartners and People With Progressive Aphasia [EARLY_Phase 1]

  An EARLY Phase 1 clinical trial at the University of Texas at Austin is evaluating an Educational Support Group Program for bilingual and Sp…

• CLINICAL_TRIALS research · 2025-03-04
  Clinical Trial Update: Investigating Genetic Status in Patients Presenting to Clinic

  A clinical trial at multiple centers is recruiting to study the genetic status of patients presenting with dementia syndromes, including fro…

• CLINICAL_TRIALS research · 2025-03-03
  Clinical Trial Update: Genetic Studies in Familial Dementia

  This completed clinical trial update reports on genetic studies investigating familial dementia and Alzheimer's-related conditions.

• CLINICAL_TRIALS research · 2025-03-03
  Clinical Trial Update: NYSCF Scientific Discovery Biobank

  Clinical trial entry for the NYSCF Scientific Discovery Biobank (NCT06203106) shows recruiting status and lists indications including amyotr…

• CLINICAL_TRIALS research · 2025-03-03
  Clinical Trial Update: Biomarkers for Monitoring Dementia Progression

  A recruiting clinical trial is studying biomarkers to monitor progression in Alzheimer's disease.

• CLINICAL_TRIALS research · 2025-02-28
  Clinical Trial Update: Designing a Tailored Primary Care Intervention to Manage the Burden of Caring for Patients Living with Alzheimer's Disease (or a Related Dementia)

  This study protocol is designed to develop and evaluate a tailored primary-care intervention to reduce caregiver burden for patients with Al…

• CLINICAL_TRIALS research · 2025-02-27
  Clinical Trial Update: Efficacy and Safety of Dimethyl Fumarate Among Patients with Mild Cognitive Impairment and Dementia Due to Alzheimer's Disease [Phase 2]

  Phase 2 clinical trial evaluating the efficacy and safety of dimethyl fumarate in patients with mild cognitive impairment and dementia due t…

• CLINICAL_TRIALS research · 2025-02-26
  Clinical Trial Update: A Study of Oral EX039 in Subjects with Mild Alzheimer's Disease [Phase 2]

  This is an update on a Phase 2 study evaluating oral EX039 for mild Alzheimer's disease, with the trial currently recruiting.

• CLINICAL_TRIALS research · 2025-02-24
  Clinical Trial Update: Biomarkers in a Candian Memory Clinic

  This clinical trial update describes biomarkers research for Alzheimer's disease at a Canadian memory clinic, with enrollment ongoing by inv…

• CLINICAL_TRIALS research · 2025-02-24
  Clinical Trial Update: Fundus Camera Module for Early Detection of Alzheimer's Disease

  A recruiting clinical trial is evaluating a fundus camera module for the early detection of Alzheimer's disease.

• CLINICAL_TRIALS research · 2025-02-21
  Clinical Trial Update: The Safety and Efficacy of Sodium Pentaborate Pentahydrate in Patients With Mild to Moderate Alzheimer's Disease [Phase 2]

  Phase 2 clinical trial evaluating the safety and efficacy of Sodium pentaborate pentahydrate in adults with mild to moderate Alzheimer's dis…

• CLINICAL_TRIALS research · 2025-02-20
  Clinical Trial Update: A Longitudinal Study to Explore the Impact of Gut Microbiome on Brain Health in Alzheimer's Disease

  This clinical trial is a longitudinal study examining the impact of the gut microbiome on brain health in Alzheimer's disease. It is current…

• CLINICAL_TRIALS research · 2025-02-19
  Clinical Trial Update: [18F]AV45(Aβ) and [18F]AV1451(Tau)PET/CT in the Diagnosis of Early Pathological Changes of Alzheimer's Disease

  A clinical trial update evaluating [18F]AV45 and [18F]AV1451 PET/CT imaging for detecting early Alzheimer's disease pathology.

• CLINICAL_TRIALS research · 2025-02-17
  Clinical Trial Update: The Role of Advanced Electroencephalographic Data as Marker of Pathology and Prognosis in Primary Dementias [NA]

  This clinical trial update notes that IRCCS San Raffaele is enrolling by invitation in a study using advanced electroencephalographic data a…

• CLINICAL_TRIALS research · 2025-02-14
  Clinical Trial Update: Nursing Interventions for Alzheimer's Patients During PET/CT Imaging [NA]

  This clinical trial is evaluating nursing interventions for Alzheimer's disease patients undergoing PET/CT imaging, and the study is current…

• CLINICAL_TRIALS research · 2025-02-13
  Clinical Trial Update: Marker of Brain Insulin Resistance in AD Prognosis [NA]

  A clinical trial in France is evaluating brain insulin resistance as a prognostic biomarker for Alzheimer's disease and mild cognitive impai…

• CLINICAL_TRIALS research · 2025-02-13
  Clinical Trial Update: Digital Twins for Model-driven Non-invasive Electrical Brain Stimulation [NA]

  Ongoing clinical trial update from I.R.C.C.S. Fondazione Santa Lucia on digital twins for model-driven non-invasive electrical brain stimula…