Alzheimer Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: Phase 3 Clinical Trial of Wujia Yizhi Granules in the Treatment of Mild-to-moderate Alzheimer's Dementia (Syndrome of Deficiency of Spleen and Kidney) [Phase 3]
Phase 3 clinical trial evaluating Wujia Yizhi Granules for mild-to-moderate Alzheimer's dementia is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-29Clinical Trial Update: [18F]NIDF PET Imaging in Tau-related Diseases
This clinical trial update reports recruitment for a study using the PET imaging tracer [18F]NIDF to visualize tau-related neurodegenerative…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Remote tDCS and Chair Yoga for Chronic Knee Pain in Alzheimer's Patients [NA]
A University of Arizona trial is recruiting to evaluate remote transcranial direct current stimulation (tDCS) and chair yoga for chronic kne…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: PMN310 in Patients With Early Alzheimer's Disease (PRECISE-AD) [Phase 1]
Phase 1 study PRECISE-AD evaluating PMN310 for early-onset Alzheimer disease is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Low-intensity Hippocampal Transcranial Ultrasound Stimulation for Managing Cognitive and Sleep Dysfunction in Preclinical Alzheimer's Disease [NA]
A clinical trial update describes enrollment for a study evaluating low-intensity hippocampal transcranial ultrasound stimulation to manage …
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CLINICAL_TRIALS research · 2025-12-23Clinical Trial Update: Incremental Diagnostic Value of Tau-PET With [18F]RO948 vs Amyloid-PET in Patients With Cognitive Impairment [NA]
This clinical trial update reports on the investigation of the incremental diagnostic value of tau-PET imaging with [18F]RO948 versus amyloi…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Exploratory Clinical Study and Validation of Blood Biomarkers for Alzheimer's Disease
An exploratory clinical study validating blood-based biomarkers for Alzheimer's disease.
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Phase II Trial to Evaluate Safety and Efficacy of GM-CSF/Sargramostim in Alzheimer's Disease [Phase 2]
A Phase II trial is evaluating the safety and efficacy of GM-CSF (sargramostim) in Alzheimer's disease and is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Time-in-bed Restriction in Older Adults With Sleep Difficulties With and Without Risk for Alzheimer's Disease [EARLY_Phase 1]
A University of Pittsburgh EARLY Phase 1 clinical trial is evaluating time-in-bed restrictions in older adults with sleep difficulties, incl…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Daridorexant for Alzheimer Disease Prevention [Phase 2]
A Phase 2 clinical trial of daridorexant for Alzheimer's disease prevention is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: The PorchLight Project [NA]
The PorchLight Project clinical trial (NCT05550727) sponsored by the University of Minnesota studies memory loss, Alzheimer's disease, and d…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: A Study of ONO-2020 in Patients With Agitation Associated With Alzheimer's Disease Dementia [Phase 2]
A Phase 2 clinical trial evaluating ONO-2020 for agitation associated with Alzheimer's disease dementia is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: A Study of Mevidalen (LY3154207) in Participants With Alzheimer's Disease [Phase 2]
This document provides an update on the Phase 2 trial of Mevidalen (LY3154207) for Alzheimer's disease, noting the study is currently active…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Deprescribing in Patients Living With Dementia With Caregiver and Provider Nudges [NA]
A completed Brigham and Women's Hospital clinical trial investigates deprescribing in people with dementia, guided by caregiver and provider…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Hearing Loss and Genetic Risks for Alzheimer's Disease and Related Dementia [NA]
This study investigates the relationship between hearing loss, genetics, and the risk of Alzheimer's disease and related dementias, sponsore…
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CLINICAL_TRIALS research · 2025-12-17Clinical Trial Update: Sleep Trial to Prevent Alzheimer's Disease [Phase 2]
A Phase 2 clinical trial is currently recruiting to evaluate whether a sleep intervention can help prevent Alzheimer's disease.
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Biomarkers of the Locus Coeruleus Nucleus: Links With Early Tau Pathology, Cognition and Alzheimer's Disease Risk [Phase 2]
This Phase 2 clinical trial update describes studying biomarkers of the locus coeruleus and their links to early tau pathology, cognition, a…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Alzheimer's Prevention Registry: A Program to Accelerate Enrollment Into Studies
The Alzheimer's Prevention Registry is a program to accelerate enrollment into Alzheimer's disease and dementia studies, sponsored by Banner…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Cholinergic Health After Menopause (CHAMP) [EARLY_Phase 1]
This entry reports completion of the CHAMP early-phase 1 trial investigating cholinergic health after menopause; the study status is now com…
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: Digital Technology Combined With Blood Marker Screening and Diagnosis for Community Populations Based on Classification Theory: an Integrated Study
This clinical trial explores digital technology combined with blood marker screening to aid diagnosis of Alzheimer’s disease in community po…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Improving Executive Control in Cognitively Healthy Older Adults: the MUltitasking STrategy (MUST) Study [NA]
This clinical trial, the MUST Study, is evaluating a multitasking strategy to improve executive control in cognitively healthy older adults.…
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study) [Phase 1, Phase 2]
This clinical trial update indicates that AC Immune's Alzheimer’s-focused candidate ACI-24.060 is being evaluated in Phase 1 and Phase 2 stu…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: NAD Augmentation to Prevent or Reverse Alzheimer's Disease in People With Down Syndrome [Phase 1]
Phase 1 clinical trial evaluating NAD augmentation to prevent or reverse Alzheimer's disease in people with Down syndrome; currently not yet…
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Combined Brain Stimulation and Methylphenidate Treatment for Apathy in Dementia [Phase 2]
Phase 2 clinical trial assessing the combination of brain stimulation and methylphenidate to treat apathy in Alzheimer’s disease/dementia, c…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: UAB Alzheimer's Disease Center Core Cohort - Imaging Substudy [Phase 2]
This clinical trial update describes a Phase 2 imaging substudy within the UAB Alzheimer's Disease Center Core Cohort. It is currently recru…