Alpha-1 Antitrypsin Deficiency

• CLINICAL_TRIALS trial_result · 2014-01-03
  Clinical Trial Update: 4-PBA: Will it Increase the Level of Alpha 1-Antitrypsin(AAT) in Persons With AAT Deficiency? [Phase 2]

  This update notes the Phase 2 trial of 4-phenylbutyrate to raise alpha-1 antitrypsin levels in individuals with alpha-1 antitrypsin deficien…

• CLINICAL_TRIALS trial_result · 2013-12-17
  Clinical Trial Update: Effects of Exercise Training in Chronic Obstructive Pulmonary Disease Versus Alpha-1-Antitrypsin-deficiency-patients [NA]

  A completed clinical trial comparing the effects of exercise training in chronic obstructive pulmonary disease patients versus those with al…

• CLINICAL_TRIALS trial_result · 2013-05-20
  Clinical Trial Update: Safety and Pharmacokinetics of Alpha-1 Proteinase Inhibitor in Subjects With Alpha1-Antitrypsin Deficiency [Phase 2]

  Phase 2 trial evaluating safety and pharmacokinetics of Alpha-1 Proteinase Inhibitor in individuals with Alpha-1 antitrypsin deficiency comp…

• CLINICAL_TRIALS trial_result · 2012-09-14
  Clinical Trial Update: Safety & Efficacy Study of rAAV1-CB-hAAT for Alpha-1 Antitrypsin Deficiency [Phase 2]

  Phase 2 clinical trial update on rAAV1-CB-hAAT for alpha-1 antitrypsin deficiency has completed with results posted in 2012.

• CLINICAL_TRIALS trial_result · 2012-01-19
  Clinical Trial Update: Prevalence of Alpha-1 Antitrypsin Deficiency in Chronic Obstructive Pulmonary Disease (COPD)

  This completed clinical trial assessed the prevalence of Alpha-1 Antitrypsin Deficiency among individuals with Chronic Obstructive Pulmonary…

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• CLINICAL_TRIALS trial_result · 2011-07-20
  Clinical Trial Update: Pharmacokinetic Study of ARALAST (Human Alpha1- PI) [Phase 1]

  Phase 1 pharmacokinetic study of ARALAST (human Alpha1-antitrypsin) in Alpha 1-Antitrypsin Deficiency was completed with results posted in 2…

• CLINICAL_TRIALS trial_result · 2011-01-04
  Clinical Trial Update: Efficacy and Safety Study of Augmentation Therapy With ARALAST Fraction IV-1 (Human Alpha 1 - Proteinase Inhibitor) [Phase 4]

  Phase 4 clinical trial update evaluating augmentation therapy with ARALAST Fraction IV-1 in Alpha 1-antitrypsin deficiency; results posted a…

• CLINICAL_TRIALS trial_result · 2007-10-17
  Clinical Trial Update: Phase II/III Study of an Alpha-1 Proteinase Inhibitor (Kamada-API) in Individuals With Alpha-1 Antitrypsin Deficiency [Phase 2, Phase 3]

  Phase II/III trial of Kamada-API, an alpha-1 proteinase inhibitor, in individuals with Alpha-1 antitrypsin deficiency has completed. The upd…