Allergic Asthma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2015-04-09Clinical Trial Update: Change in Airway Responsiveness After Allergen Exposure [NA]
This update reports the completion of a study evaluating changes in airway responsiveness after allergen exposure in individuals with allerg…
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CLINICAL_TRIALS withdrawal · 2015-03-27Clinical Trial Update: Role of Indoor Pollutants on House Dust Mite Allergic Asthma [NA]
This clinical trial update indicates that the NCT01019291 study on indoor pollutants and house dust mite–related allergic asthma has been wi…
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CLINICAL_TRIALS trial_result · 2015-03-27Clinical Trial Update: Validation of Proteomic Analyses for Allergic Asthma and Rhinitis
This completed clinical trial assesses proteomic analyses in allergic asthma and allergic rhinitis.
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CLINICAL_TRIALS trial_result · 2015-03-06Clinical Trial Update: Extracorporeal SPecific IgE Removal From the Plasma of Allergic Asthma Patients (ESPIRA-study) [NA]
The ESPIRA study, which evaluated extracorporeal removal of specific IgE from plasma in allergic asthma patients, has completed.
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CLINICAL_TRIALS trial_result · 2014-12-30Clinical Trial Update: A Phase 1, Randomized, Placebo-controlled, Dose-escalation Safety Study of MEDI4212 in Subjects With IgE >= 30 IU/mL [Phase 1]
Phase 1 randomized, placebo-controlled, dose-escalation safety study of MEDI4212 in subjects with IgE ≥ 30 IU/mL has completed and results h…
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CLINICAL_TRIALS trial_result · 2014-11-13Clinical Trial Update: 2nd Pivotal Study rPhleum - Adults and Adolescents With Rhinoconjunctivitis +/-Controlled Asthma [Phase 3]
A Phase 3 pivotal trial of recombinant Timothy grass allergen (rPhleum) in adults and adolescents with rhinoconjunctivitis with or without c…
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CLINICAL_TRIALS trial_result · 2014-10-15Clinical Trial Update: A Study Evaluating the Persistency of Response With or Without Xolair (Omalizumab) After Long-term Therapy [Phase 4]
Phase 4 study evaluating the persistence of response after long-term omalizumab therapy in allergic asthma, comparing continued treatment wi…
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CLINICAL_TRIALS trial_result · 2014-08-12Clinical Trial Update: The Role of Th9 Cells and Eosinophils Activity in Allergic Airway Diseases
A clinical trial update examines the role of TH9 cells and eosinophil activity in allergic airway diseases, including allergic asthma and al…
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CLINICAL_TRIALS trial_result · 2014-05-14Clinical Trial Update: CYT003-QbG10, a TLR9-agonist, for Treatment of Uncontrolled Moderate to Severe Allergic Asthma [Phase 2]
This update reports the termination of a Phase 2 study of CYT003-QbG10, a TLR9 agonist, for treatment of uncontrolled moderate to severe all…
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CLINICAL_TRIALS trial_result · 2013-11-20Clinical Trial Update: Study to Evaluate the Safety and Efficacy TPI ASM8 in Subjects With Asthma [Phase 2]
A Phase 2 study evaluating the safety and efficacy of TPI ASM8 in allergic asthma has completed.
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CLINICAL_TRIALS research · 2013-01-28Clinical Trial Update: The REALITY Study - a Real-life Long-term Analysis of Xolair Therapy
This document provides an update on the REALITY study, a real-world, long-term analysis of omalizumab (Xolair) therapy for allergic asthma.
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CLINICAL_TRIALS trial_result · 2013-01-18Clinical Trial Update: Efficacy of Omalizumab in Adults (18-60 Years of Age) With Moderate-Severe, Persistent Allergic Asthma, Despite Receiving Inhaled Corticosteroids and Long Acting Beta-agonists [Phase 4]
Phase 4 trial results evaluate the efficacy of omalizumab in adults aged 18-60 with moderate-to-severe persistent allergic asthma who remain…
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CLINICAL_TRIALS trial_result · 2012-08-15Clinical Trial Update: Optimization of Asthma Treatment Through Exhaled NO for Increased Asthma-Related Quality of Life (NOAK) [NA]
This entry notes the completion of a trial studying exhaled nitric oxide-guided asthma treatment (NOAK) for allergic asthma. The sponsor is …
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CLINICAL_TRIALS trial_result · 2012-01-19Clinical Trial Update: Utility of Versican and Hyaluronan Measurement in Induced Sputum as Biomarkers of Asthma [Phase 4]
This Phase 4 clinical trial evaluated whether measuring versican and hyaluronan in induced sputum can serve as biomarkers for asthma.
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CLINICAL_TRIALS trial_result · 2011-11-24Clinical Trial Update: Induction of Allergen Specific Bronchial Immunotolerance After Specific Immunotherapy
This completed clinical trial evaluated whether induction of allergen-specific bronchial immunotolerance can be achieved after specific immu…
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CLINICAL_TRIALS other · 2011-11-07Clinical Trial Update: In Vitro Basophil Responsiveness to Allergen Challenge After Gamma-tocopherol Supplementation in Allergic Asthmatics [Phase 1]
This clinical trial update reports a Phase 1 study evaluating in vitro basophil responsiveness to allergen challenge after gamma-tocopherol …
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CLINICAL_TRIALS trial_result · 2011-10-12Clinical Trial Update: Safety and Repeatability of Bronchial Challenge With Grass-pollen
This clinical trial update assesses the safety and repeatability of performing bronchial challenges with grass pollen in individuals with al…
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CLINICAL_TRIALS research · 2011-09-23Clinical Trial Update: Effect of Xolair on Airway Hyperresponsiveness [Phase 4]
Phase 4 study evaluating whether Xolair (omalizumab) improves airway hyperresponsiveness in allergic asthma.
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CLINICAL_TRIALS research · 2011-09-23Clinical Trial Update: Effect of Montelukast on Basophils, In-vitro
This document reports an in vitro study evaluating the effects of montelukast on basophils. It relates to allergic asthma and allergic rhini…
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CLINICAL_TRIALS trial_result · 2011-06-03Clinical Trial Update: Efficacy/ Safety of Omalizumab in Patients With Seasonal Allergic Asthma and Seasonal Allergic Rhinoconjunctivitis [Phase 3]
Phase 3 trial evaluating efficacy and safety of omalizumab in seasonal allergic asthma and seasonal allergic rhinoconjunctivitis has complet…
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CLINICAL_TRIALS trial_result · 2011-05-16Clinical Trial Update: Study to Evaluate the Effect of Omalizumab on Improving the Tolerability of Specific Immunotherapy in Patients With Persistent Allergic Asthma [Phase 4]
A Phase 4 study evaluated whether omalizumab improves the tolerability of specific immunotherapy in patients with persistent allergic asthma…
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CLINICAL_TRIALS trial_result · 2010-05-26Clinical Trial Update: A Study of Omalizumab in the Prevention of Allergen Induced Airway Obstruction in Adults With Mild Allergic Asthma [Phase 2]
Phase 2 trial evaluating omalizumab for prevention of allergen-induced airway obstruction in adults with mild allergic asthma completed; res…
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CLINICAL_TRIALS trial_result · 2010-05-06Clinical Trial Update: A Study to Evaluate MILR1444A in the Prevention of Allergen-Induced Airway Obstruction in Adults With Mild Allergic Asthma [Phase 2]
This document provides an update on a Phase 2 study evaluating MILR1444A to prevent allergen-induced airway obstruction in adults with mild …
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FDA approval · 2010-01-04FDA Approved: XOLAIR — Supplemental Application (Genentech, Inc.)
FDA approved Genentech's supplemental application for XOLAIR (omalizumab), updating its labeling via a supplemental approval.
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CLINICAL_TRIALS trial_result · 2009-10-21Clinical Trial Update: Role of RhuMab-E25 in Reducing Exhaled Nitric Oxide (NO) in Allergic Asthma [Phase 3]
Phase 3 trial evaluated RhuMab-E25 for reducing exhaled nitric oxide in allergic asthma; results were posted in 2009.