Alcohol Dependence
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-07-15Clinical Trial Update: HBPL Study of the Impact of the NK1 Antagonist Aprepitant [Phase 2]
Phase 2 clinical trial assessing the NK1 antagonist aprepitant for cocaine and alcohol dependence has completed with posted results.
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CLINICAL_TRIALS trial_result · 2020-06-16Clinical Trial Update: Extended-Release vs. Oral Naltrexone Alcohol Treatment in Primary Care [Phase 4]
Phase 4 trial comparing extended-release versus oral naltrexone for alcohol dependence conducted in primary care; results posted after compl…
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CLINICAL_TRIALS withdrawal · 2020-04-02Clinical Trial Update: Couples-based Behavioral Psychotherapy for Male Patients With Posttraumatic Stress Disorder and Alcohol Dependence [Phase 2, Phase 3]
A clinical trial evaluating couples-based behavioral psychotherapy for men with PTSD and alcohol dependence was withdrawn.
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CLINICAL_TRIALS research · 2020-04-02Clinical Trial Update: Alcohol Counseling for Telephone Quitline Callers [Phase 1, Phase 2]
A clinical trial exploring alcohol counseling for callers to a quitline, conducted in Phase 1 and Phase 2 with outcomes related to smoking a…
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CLINICAL_TRIALS trial_result · 2020-03-16Clinical Trial Update: Zonisamide in Addition to E-CPT-C for Veterans With PTSD and Comorbid Alcohol Dependence [Phase 2]
Phase 2 trial evaluating zonisamide added to E-CPT-C for veterans with PTSD and alcohol dependence has completed; results posted.
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CLINICAL_TRIALS trial_result · 2020-03-12Clinical Trial Update: 10 Days of Theta Burst Stimulation as a Tool to Treat Cocaine Dependence [Phase 2]
Phase 2 clinical trial investigating theta burst stimulation to treat cocaine and alcohol dependence has completed.
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CLINICAL_TRIALS trial_result · 2020-02-13Clinical Trial Update: Treatment for Alcohol Dependence With Gabapentin [Phase 4]
Phase 4 clinical trial update for gabapentin in alcohol dependence; the study is terminated.
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CLINICAL_TRIALS trial_result · 2020-02-11Clinical Trial Update: Integrated Treatment of OEF/OIF Veterans With PTSD & Substance Use Disorders [NA]
Clinical trial update on integrated treatment for veterans with PTSD and co-occurring substance use disorders; completed with results posted…
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CLINICAL_TRIALS trial_result · 2019-09-30Clinical Trial Update: A Multicenter, Randomized, Double-blind, Placebo-controlled, 3-parallel-group Comparison Trial to Investigate the Effect of Nalmefene on Alcohol Consumption Reduction in Patients With Alcohol Dependence (Phase 3 Trial) [Phase 3]
Phase 3 randomized trial evaluating nalmefene for reducing alcohol consumption in adults with alcohol dependence; results posted after compl…
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CLINICAL_TRIALS trial_result · 2019-09-09Clinical Trial Update: Health Behavior Change for Hospitalized Veterans [NA]
A terminated clinical trial evaluating health behavior change for alcohol consumption among hospitalized veterans; results posted in 2019.
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FDA approval · 2019-09-06FDA Approved: VIVITROL — Supplemental Application (Alkermes, Inc.)
FDA approved a supplemental application for VIVITROL (naltrexone) from Alkermes, Inc., resulting in an updated/expanded approval.
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CLINICAL_TRIALS trial_result · 2019-07-25Clinical Trial Update: Alcohol Screening, Brief Intervention, and Referral to Treatment in a Military Treatment Facility [NA]
Completed clinical trial evaluating alcohol screening, brief intervention, and referral to treatment in a military setting; results posted i…
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CLINICAL_TRIALS trial_result · 2019-07-23Clinical Trial Update: Citalopram Effects on Craving and Dopamine Receptor Availability in Alcoholics [Phase 1]
Phase 1 trial investigating citalopram's effects on craving and dopamine receptor availability in individuals with alcohol dependence; study…
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CLINICAL_TRIALS trial_result · 2019-05-22Clinical Trial Update: Efficacy and Safety Evaluating Study of Odelepran for the Use in Patient With Alcohol Dependence [Phase 3]
Phase 3 clinical trial evaluating the efficacy and safety of Odelepran for alcohol dependence has completed.
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CLINICAL_TRIALS trial_result · 2019-04-26Clinical Trial Update: Dutasteride Treatment for the Reduction of Heavy Drinking in Men [Phase 4]
A Phase 4 clinical trial evaluated dutasteride as a treatment to reduce heavy drinking in men with alcoholism/alcohol dependence; results co…
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CLINICAL_TRIALS trial_result · 2019-04-23Clinical Trial Update: Glutamatergic Modulation of Disordered Alcohol Use [Phase 2, Phase 3]
Phase 2/3 clinical trial update on glutamatergic modulation for alcohol dependence; completed with results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-04-10Clinical Trial Update: Safety and Pharmacodynamic Study of GET 73 in Alcohol Dependent [Phase 1, Phase 2]
A safety and pharmacodynamic study of GET 73 in alcohol dependence has completed Phase 1 and Phase 2 trials.
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CLINICAL_TRIALS trial_result · 2019-03-19Clinical Trial Update: The Efficacy and Neurobehavioural Mechanism of N-acetyl Cysteine (NAC) for Alcohol Dependence [Phase 2]
Phase 2 study investigating the efficacy and neurobehavioral mechanism of N-acetylcysteine (NAC) for alcohol dependence.
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CLINICAL_TRIALS trial_result · 2019-03-05Clinical Trial Update: Oral vs. Injectable Naltrexone for Hospitalized Veterans With Alcohol Dependence [Phase 3]
Phase 3 trial comparing oral versus injectable naltrexone for alcohol dependence in hospitalized veterans has completed with results posted.
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CLINICAL_TRIALS research · 2019-02-01Clinical Trial Update: Neurofeedback & Alcohol Dependence [NA]
A completed clinical trial evaluating neurofeedback as a treatment for alcohol dependence.
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CLINICAL_TRIALS trial_result · 2019-01-09Clinical Trial Update: Treatment of Alcohol Dependence and Comorbid Bipolar Disorder [Phase 4]
Phase 4 clinical trial updating treatment for alcohol dependence with comorbid bipolar disorder; results posted after completion.
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CLINICAL_TRIALS trial_result · 2019-01-08Clinical Trial Update: Efficacy and Safety of High Dose Baclofen for Alcohol Dependence [Phase 2]
Phase 2 trial update on high-dose baclofen for alcohol dependence with efficacy and safety results posted.
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CLINICAL_TRIALS trial_result · 2018-12-14Clinical Trial Update: Acamprosate vs. Placebo in Bipolar Alcoholics [Phase 4]
Phase 4 trial comparing acamprosate to placebo in individuals with alcohol dependence and bipolar disorder; study completed with results pos…
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CLINICAL_TRIALS trial_result · 2018-08-03Clinical Trial Update: Ghrelin for Alcohol Use in Non-Treatment-Seeking Heavy Drinkers [Phase 2]
Phase 2 trial evaluating ghrelin for reducing alcohol use in heavy drinkers who are not seeking treatment; study completed with results post…
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CLINICAL_TRIALS trial_result · 2018-07-24Clinical Trial Update: Citicoline for Alcohol Dependence [Phase 4]
A Phase 4 clinical trial evaluating citicoline for alcohol dependence has completed, with results posted in 2018.