Adrenal Insufficiency
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2014-07-14Clinical Trial Update: Hydrocortisone Replacement in Patients With Secondary Adrenal Insufficiency (SUPREME CORT) [Phase 4]
Phase 4 SUPREME CORT trial evaluating hydrocortisone replacement in patients with secondary adrenal insufficiency has completed and posted r…
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CLINICAL_TRIALS trial_result · 2014-06-16Clinical Trial Update: Adrenal Responsiveness During the Perioperative Period in Children Undergoing Congenital Cardiac Surgery [Phase 1]
Phase 1 study assessing adrenal responsiveness during the perioperative period in children undergoing congenital cardiac surgery; the trial …
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CLINICAL_TRIALS trial_result · 2014-01-06Clinical Trial Update: Prospective Study on the Incidence of Adrenal Crisis in Patients With Chronic Adrenal Insufficiency
A prospective, completed study investigating how often adrenal crisis occurs in patients with chronic adrenal insufficiency.
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CLINICAL_TRIALS trial_result · 2014-01-06Clinical Trial Update: Counterregulatory Hormone Production in Adrenal Insufficiency and Diabetes Type I
A completed clinical trial update examining counterregulatory hormone production in individuals with adrenal insufficiency, Addison's diseas…
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CLINICAL_TRIALS withdrawal · 2013-09-05Clinical Trial Update: Gene Polymorphisms Influencing Steroid Synthesis and Action
A clinical trial investigating how gene polymorphisms influence steroid synthesis and action has been withdrawn.
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CLINICAL_TRIALS trial_result · 2013-08-26Clinical Trial Update: Single Dose of Etomidate and Adrenal Cortex [Phase 4]
Phase 4 update on a single-dose etomidate protocol in patients with adrenal insufficiency and hemodynamic instability.
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CLINICAL_TRIALS trial_result · 2013-03-11Clinical Trial Update: Cortisol Response to Moderate and Deep Sedation in Children
This clinical trial update reports results on cortisol response to moderate and deep sedation in children with adrenal insufficiency.
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CLINICAL_TRIALS safety_alert · 2013-02-26Clinical Trial Update: Intra-articular Betamethasone and the Hypothalamic-pituitary-adrenal Axis
A completed clinical trial assessed the risk of hypothalamic-pituitary-adrenal axis suppression following intra-articular betamethasone inje…
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CLINICAL_TRIALS trial_result · 2013-02-06Clinical Trial Update: Revival of Stem Cells in Addison's Study [Phase 4]
A Phase 4 trial at Newcastle University evaluating stem cell therapy for Addison's disease (adrenal failure) has completed.
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CLINICAL_TRIALS research · 2012-10-10Clinical Trial Update: The Significance of Defensin Alpha 4 in the Pathophysiology of the Adrenal Insufficiency in Inflammatory Lung Diseases
This clinical trial update investigates the role of defensin alpha-4 in the pathophysiology of adrenal insufficiency in inflammatory lung di…
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CLINICAL_TRIALS trial_result · 2012-08-01Clinical Trial Update: Pharmacokinetics of Hydrocortisone After Subcutaneous Administration in Chronic Adrenal Insufficiency [Phase 2]
Phase 2 clinical trial update examining the pharmacokinetics of subcutaneously administered hydrocortisone in chronic adrenal insufficiency.
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FDA approval · 2012-06-29FDA Approved: COSYNTROPIN — Original Application (Sandoz Inc)
FDA approves a generic cosyntropin injection (Cosyntropin) under an Original Application by Sandoz Inc.
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CLINICAL_TRIALS withdrawal · 2012-02-13Clinical Trial Update: Hydrocortisone Versus Hydrocortisone Plus Fludrocortisone for the Treatment of Adrenal Insufficiency in Severe Sepsis [Phase 4]
This Phase 4 clinical trial comparing hydrocortisone alone versus hydrocortisone plus fludrocortisone for adrenal insufficiency in severe se…
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CLINICAL_TRIALS safety_alert · 2011-08-29Clinical Trial Update: Adrenal Suppression and Adrenal Recovery Induced by Megestrol Acetate [NA]
The trial update reports adrenal suppression associated with megestrol acetate, with adrenal recovery observed after discontinuation.
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CLINICAL_TRIALS research · 2011-08-09Clinical Trial Update: Test Predicting Adrenal Insufficiency in Volunteers Under Prednisone Treatment [Phase 4]
Phase 4 clinical trial evaluating a test to predict adrenal insufficiency in volunteers treated with prednisone; the study has completed.
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CLINICAL_TRIALS trial_result · 2011-06-29Clinical Trial Update: Adrenal Insufficiency in Septic Shock [Phase 4]
A Phase 4 clinical trial evaluating adrenal insufficiency in septic shock has been terminated. The study was sponsored by The Methodist Hosp…
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CLINICAL_TRIALS other · 2011-05-23Clinical Trial Update: DHEA Replacement in Adrenalectomized/Hypoadrenal Patients [NA]
Clinical trial update from Mayo Clinic on DHEA replacement in adrenalectomized or hypoadrenal patients; the study status is completed.
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CLINICAL_TRIALS trial_result · 2009-11-25Clinical Trial Update: Adrenal Exhaustion Syndrome in Critically Ill Patients Without Improvement
The study reports completion of a clinical trial on adrenal exhaustion syndrome in critically ill patients, focusing on survival outcomes wh…
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CLINICAL_TRIALS trial_result · 2009-11-11Clinical Trial Update: Evaluation of Etomidate on Adrenal Function in Trauma Patients [NA]
This clinical trial update reports the completed study evaluating the impact of etomidate on adrenal function in trauma patients. The trial,…
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CLINICAL_TRIALS research · 2009-02-18Clinical Trial Update: Effect of Treatment With Stress-Doses Glucocorticoid in Patients With Acute Respiratory Distress Syndrome (ARDS) [Phase 4]
This entry summarizes a Phase 4 clinical trial evaluating stress-dose glucocorticoids in patients with Acute Respiratory Distress Syndrome, …
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CLINICAL_TRIALS trial_result · 2009-01-16Clinical Trial Update: Adrenal Function in Patients With Newly Diagnosed Lung Cancer
A completed clinical trial evaluating adrenal function in patients with newly diagnosed lung cancer.
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CLINICAL_TRIALS trial_result · 2008-04-14Clinical Trial Update: Adrenal Insufficiency in Cirrhotics With Ascites. Effects of Hydrocortisone on Renal and Haemodynamic Function [Phase 2]
This Phase 2 clinical trial from the University of Turin investigates whether hydrocortisone improves renal and haemodynamic function in pat…
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CLINICAL_TRIALS trial_result · 2008-03-04Clinical Trial Update: Dose Response Relationship for Single Doses of Corticotropin Releasing Hormone (CRH) in Normal Volunteers and in Patients With Adrenal Insufficiency
Clinical trial update evaluating the dose-response of single doses of corticotropin releasing hormone (CRH) in healthy volunteers and patien…
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CLINICAL_TRIALS trial_result · 2007-12-18Clinical Trial Update: Dehydroepiandrosterone Substitution in Adolescent and Young Women With Central Adrenal Insufficiency [Phase 3]
This Phase 3 trial evaluated dehydroepiandrosterone (DHEA) substitution in adolescents and young women with central adrenal insufficiency; t…
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FDA approval · 2007-11-28FDA Approved: HYDROCORTISONE — Supplemental Application (Padagis Israel Pharmaceuticals Ltd)
FDA approved a supplemental application for Hydrocortisone by Padagis Israel Pharmaceuticals Ltd, indicating an update to the product's appr…