Respiratory Distress Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-03-13Clinical Trial Update: Nalbuphine in ARDS Patients After Surgery [Phase 4]
Phase 4 clinical trial evaluating nalbuphine in patients with acute respiratory distress syndrome after surgery is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-03-13Clinical Trial Update: Sedative Effect and Safety of Remimazolam Besylate in ARDS Patients [Phase 4]
Phase 4 clinical trial update evaluating sedative effect and safety of remimazolam besylate in patients with respiratory distress syndrome.
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CLINICAL_TRIALS trial_result · 2024-03-07Clinical Trial Update: A Study to Test Whether Different Doses of Alteplase Help People With Severe Breathing Problems Because of COVID-19 [Phase 2, Phase 3]
A study evaluating different doses of alteplase for severe respiratory problems due to COVID-19 has completed phases 2 and 3, with results p…
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CLINICAL_TRIALS trial_result · 2024-03-06Clinical Trial Update: Volatile Sedation for Patients With the Acute Respiratory Distress Syndrome [Phase 2, Phase 3]
A trial update for volatile sedation in acute respiratory distress syndrome patients on mechanical ventilation across Phase 2 and Phase 3.
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: Clinical Study to Assess the Safety and Preliminary Efficacy of HCR040 in Acute Respiratory Distress Syndrome [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluated safety and preliminary efficacy of HCR040 in acute respiratory distress syndrome (ARDS).
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CLINICAL_TRIALS trial_result · 2024-01-31Clinical Trial Update: Lessening Organ Dysfunction With VITamin C in Septic ARDS [Phase 3]
Phase 3 trial investigating high-dose vitamin C to reduce organ dysfunction in septic acute respiratory distress syndrome (ARDS).
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CLINICAL_TRIALS trial_result · 2024-01-05Clinical Trial Update: A Phase 2/3 Study to Evaluate FP-025 in Patients With Severe to Critical COVID 19 [Phase 2, Phase 3]
A Phase 2/3 study of FP-025 in severe to critical COVID-19 with ARDS was terminated; results were posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-01-03Clinical Trial Update: Procollagen-3 Driven Corticosteroids for Persistent Acute Respiratory Distress Syndrome [Phase 3]
Phase 3 trial of procollagen-3 driven corticosteroids for persistent acute respiratory distress syndrome has been terminated.
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CLINICAL_TRIALS trial_result · 2023-11-03Clinical Trial Update: A Study in Preterm Neonates With Respiratory Distress Syndrome (RDS) Comparing CUROSURF® Administration Through Less Invasive Surfactant Administration (LISA) and Conventional Administration [Phase 3]
Phase 3 study comparing CUROSURF administration via less invasive surfactant administration (LISA) versus conventional administration in pre…
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CLINICAL_TRIALS trial_result · 2023-11-01Clinical Trial Update: Zofin (Organicell Flow) for Patients With COVID-19 [Phase 1, Phase 2]
Clinical trial update for Zofin (Organicell Flow) in COVID-19 patients, reporting Phase 1 and Phase 2 completion.
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CLINICAL_TRIALS trial_result · 2023-10-12Clinical Trial Update: Electrical Impedance Tomography for Optimization of Positive End-Expiratory Pressure: Acute Respiratory Distress Syndrome [NA]
Clinical trial assessing electrical impedance tomography to optimize PEEP in patients with acute respiratory distress syndrome has completed…
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CLINICAL_TRIALS trial_result · 2023-10-10Clinical Trial Update: Effect of Bronchoscopy on the Outcome of Patients With Severe Sepsis With ARDS and Complicated by VAP From Prolonged Ventilation [Phase 1, Phase 2]
A two-phase clinical trial evaluated the effect of bronchoscopy on outcomes in patients with severe sepsis, ARDS, septic shock, and prolonge…
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CLINICAL_TRIALS trial_result · 2023-10-10Clinical Trial Update: Effect of Bronchoscopy on the Outcome of Patients With Severe Sepsis With ARDS and Complicated by VAP From Prolonged Ventilation [Phase 1, Phase 2]
A combined Phase 1/2 trial evaluated bronchoscopy in patients with severe ARDS and septic shock complicated by ventilator-associated pneumon…
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CLINICAL_TRIALS trial_result · 2023-09-28Clinical Trial Update: 5-HT3 Receptor Antagonist and Respiratory Drive in Patients With ARDS [Phase 4]
Phase 4 clinical trial investigating a 5-HT3 receptor antagonist and its effect on respiratory drive in patients with acute respiratory dist…
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CLINICAL_TRIALS trial_result · 2023-08-31Clinical Trial Update: Granulocyte Macrophage-Colony Stimulating Factor (GM-CSF) Inhalation to Improve Host Defense and Pulmonary Barrier Restoration [Phase 2]
Phase 2 clinical trial evaluating inhaled GM-CSF to improve host defense and pulmonary barrier restoration in acute respiratory distress syn…
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CLINICAL_TRIALS trial_result · 2023-08-21Clinical Trial Update: Extracellular Vesicles From Mesenchymal Cells in the Treatment of Acute Respiratory Failure [Phase 1, Phase 2]
A phase 1/2 clinical trial is investigating extracellular vesicles derived from mesenchymal cells for treating acute respiratory failure, in…
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CLINICAL_TRIALS trial_result · 2023-07-27Clinical Trial Update: Safety and Efficacy of EXO-CD24 in Preventing Clinical Deterioration in Patients With Mild-Moderate ARDS [Phase 2]
Phase 2 clinical trial update on EXO-CD24 for preventing deterioration in patients with mild to moderate ARDS.
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CLINICAL_TRIALS withdrawal · 2023-07-25Clinical Trial Update: LIBERATE Trial in COVID-19 [Phase 4]
A Phase 4 clinical trial (LIBERATE) investigating COVID-19 has been withdrawn.
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CLINICAL_TRIALS trial_result · 2023-07-24Clinical Trial Update: Intravenous Aviptadil for Critical COVID-19 With Respiratory Failure [Phase 2, Phase 3]
Phase 2/3 clinical trial update for intravenous aviptadil in adults with critical COVID-19 and respiratory failure, including ARDS, with com…
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CLINICAL_TRIALS trial_result · 2023-06-23Clinical Trial Update: The Safety and Preliminary Tolerability of Lyophilized Lucinactant in Adults With Coronavirus Disease 2019 (COVID-19) [Phase 2]
Phase 2 trial assessing safety and preliminary tolerability of lyophilized lucinactant in adults with COVID-19-related acute lung injury/ARD…
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CLINICAL_TRIALS trial_result · 2023-06-23Clinical Trial Update: Poractant Alfa (Curosurf®)) -- Effect in Adult Patients Diagnosed With 2019 Novel Coronavirus (SARS-COV-19; (Covid-19)) Acute Respiratory Distress Syndrome (ARDS) [Phase 2]
Phase 2 trial updating on poractant alfa (Curosurf) for adults with ARDS due to COVID-19; the study is terminated with results posted.
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CLINICAL_TRIALS trial_result · 2023-06-22Clinical Trial Update: Efficacy and Safety of Anakinra in Acute Respiratory Distress Syndrome [Phase 2]
Phase 2 trial update examining the efficacy and safety of anakinra in Acute Respiratory Distress Syndrome.
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CLINICAL_TRIALS trial_result · 2023-06-08Clinical Trial Update: Evaluation of the Safety and Efficacy of Razuprotafib in Hospitalized Subjects With Coronavirus Disease 2019 [Phase 2]
Phase 2 trial evaluating Razuprotafib in hospitalized COVID-19 patients was terminated; results posted without move to later-phase approval.
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CLINICAL_TRIALS trial_result · 2023-06-05Clinical Trial Update: Tregs for the Treatment of Acute Respiratory Distress Syndrome (ARDS) Associated With COVID-19 (regARDS) [Phase 1]
Phase 1 trial evaluating regulatory T cells for ARDS associated with COVID-19; study terminated with results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-05-30Clinical Trial Update: Intratracheal Budesonide/Surfactant Prevents BPD [Phase 4]
Phase 4 trial updating on intratracheal budesonide with surfactant for prevention of bronchopulmonary dysplasia in respiratory distress synd…