Respiratory Distress Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-12-21Clinical Trial Update: Interobserver Variation in Applying a Radiographic Definition for Acute Respiratory Distress Syndrome (ARDS)
This clinical trial update reports interobserver variation in applying radiographic criteria for Acute Respiratory Distress Syndrome, highli…
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CLINICAL_TRIALS trial_result · 2012-11-29Clinical Trial Update: PEEP Guided by Esophageal Balloon Measurement and Its Effect on Recruitment Maneuver [NA]
This entry reports a clinical trial update evaluating whether PEEP guided by esophageal balloon measurements affects recruitment maneuvers i…
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CLINICAL_TRIALS trial_result · 2012-11-08Clinical Trial Update: Minimally Invasive Surfactant Therapy Followed by CPAP (MISTCPAP) in Preterm Infants With RDS [Phase 2]
This document describes a Phase 2 clinical trial evaluating minimally invasive surfactant therapy followed by CPAP (MISTCPAP) in preterm inf…
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CLINICAL_TRIALS trial_result · 2012-10-26Clinical Trial Update: The Relationship Between Positive End Expiratory Pressure and Cardiac Index in Patients With Acute Respiratory Distress Syndrome (ARDS) Managed on a Fluid Protocol
A completed clinical trial from Yale University investigated how positive end-expiratory pressure (PEEP) relates to cardiac index in acute r…
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CLINICAL_TRIALS trial_result · 2012-09-19Clinical Trial Update: ETCare: Safety and Preliminary Efficacy Trial [EARLY_Phase 1]
Completed Phase 1 trial of ETCare in newborn respiratory distress syndrome, reporting safety data and preliminary efficacy signals.
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CLINICAL_TRIALS trial_result · 2012-09-12Clinical Trial Update: The Effect of High Frequency Oscillation on Biological Markers of Lung Injury
This clinical trial update notes that the study evaluating the effect of high-frequency oscillation on biological markers of lung injury in …
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CLINICAL_TRIALS trial_result · 2012-08-10Clinical Trial Update: Iloprost Effects on Gas Exchange and Pulmonary Mechanics [Phase 1]
Phase 1 trial update evaluating inhaled iloprost for effects on gas exchange and pulmonary mechanics in acute respiratory distress syndrome …
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CLINICAL_TRIALS trial_result · 2012-07-24Clinical Trial Update: Calfactant for Direct Acute Respiratory Distress Syndrome [Phase 3]
Phase 3 trial of calfactant for direct acute respiratory distress syndrome was terminated; no trial results are provided in the update.
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CLINICAL_TRIALS trial_result · 2012-06-22Clinical Trial Update: Observational Crossover Study Comparing Oxygenation and Ventilation Using SiPAP Versus CPAP in LBW Infants
A completed observational crossover trial comparing SiPAP and CPAP for oxygenation and ventilation in very low birth weight infants.
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CLINICAL_TRIALS trial_result · 2012-06-13Clinical Trial Update: SURFAXIN® Treatment for Prevention of Bronchopulmonary Dysplasia (BPD) in Very Low Birth Weight (VLBW) Infants. [Phase 2]
Phase 2 trial of SURFAXIN (lucinactant) for the prevention of bronchopulmonary dysplasia in very low birth weight infants was terminated; re…
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CLINICAL_TRIALS trial_result · 2012-06-13Clinical Trial Update: Feasibility Study of Aerosolized Surfaxin in the Prevention of Respiratory Distress Syndrome (RDS) in Premature Infants [Phase 2]
Phase 2 feasibility trial of aerosolized lucinactant (Surfaxin) for prevention of respiratory distress syndrome in premature infants was ter…
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CLINICAL_TRIALS trial_result · 2012-06-12Clinical Trial Update: Predictors for Responsiveness to Corticosteroid in Patients With Early Acute Respiratory Distress Syndrome
The clinical trial evaluating predictors of response to corticosteroids in early Acute Respiratory Distress Syndrome has been terminated.
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CLINICAL_TRIALS trial_result · 2012-04-27Clinical Trial Update: KL₄Surfactant Treatment in Patients With ARDS [Phase 2]
Phase 2 clinical trial update for KL₄Surfactant in acute respiratory distress syndrome (ARDS) has terminated with results posted.
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CLINICAL_TRIALS trial_result · 2012-04-10Clinical Trial Update: Perfluorocarbon (PFC) Inhalation Treatment of Acute Lung Injury/Acute Respiratory Distress Syndrome [Phase 2]
Phase 2 clinical trial update of inhaled perfluorocarbon for adults with acute lung injury and acute respiratory distress syndrome; the curr…
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CLINICAL_TRIALS trial_result · 2012-03-08Clinical Trial Update: Respiratory Mechanics and Pleural Effusion
This entry notes the completion of a clinical trial on respiratory mechanics and pleural effusion in critically ill patients, including thos…
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CLINICAL_TRIALS trial_result · 2012-02-10Clinical Trial Update: Will CPAP Reduce Length Of Respiratory Support In Premature Infants? [Phase 3]
This Phase 3 trial evaluating CPAP in premature infants has been terminated. The study examined whether continuous positive airway pressure …
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CLINICAL_TRIALS trial_result · 2011-12-21Clinical Trial Update: High-frequency Oscillatory Ventilation (HFOV) in Preterm Infants With Severe Respiratory Distress Syndrome (RDS) [Phase 2]
A Phase 2 trial evaluating high-frequency oscillatory ventilation in preterm infants with severe respiratory distress syndrome has completed…
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CLINICAL_TRIALS trial_result · 2011-12-01Clinical Trial Update: How to Predict Lung Recruitment at the Bedside in Patients Affected by Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS)
Final status of a clinical trial evaluating bedside methods to predict lung recruitment in patients with acute lung injury/acute respiratory…
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CLINICAL_TRIALS trial_result · 2011-12-01Clinical Trial Update: The Specific Elastance in Acute Lung Injury/Acute Respiratory Distress Syndrome (ALI/ARDS) Patients [NA]
Clinical trial evaluating the specific elastance in patients with acute lung injury and ARDS has completed. The document snippet does not pr…
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CLINICAL_TRIALS trial_result · 2011-11-23Clinical Trial Update: PEEP Recruitment-comparison Between Ultrasonographic Assessment and LIP Assessment
A completed trial comparing ultrasonographic assessment with LIP assessment for guiding PEEP recruitment in acute respiratory distress syndr…
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CLINICAL_TRIALS trial_result · 2011-11-17Clinical Trial Update: Safety, Pk and Anti-inflammatory Effects of CC10 Protein in Premature Infants With Respiratory Distress Syndrome (RDS) [Phase 1, Phase 2]
This clinical trial update reports safety, pharmacokinetics, and anti-inflammatory effects of CC10 protein in premature infants with respira…
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CLINICAL_TRIALS trial_result · 2011-11-04Clinical Trial Update: Effect of Enteral Nutrition Support for Critically Ill Patients [Phase 3]
A Phase 3 trial evaluating enteral nutrition support for critically ill adults with respiratory distress syndrome or acute lung injury was t…
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CLINICAL_TRIALS trial_result · 2011-10-03Clinical Trial Update: A Phase II Randomized Trial of Fish Oil in Patients With Acute Lung Injury (ALI) [Phase 2]
A Phase II randomized trial tested fish oil (omega-3 fatty acids) in adults with acute lung injury, including acute respiratory distress syn…
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CLINICAL_TRIALS trial_result · 2011-09-20Clinical Trial Update: Curosurf and Survanta Treatment(CAST)of RDS in Very Premature Infants [Phase 4]
Phase 4 CAST trial updating the use of Curosurf (poractant alfa) and Survanta (beractant) for respiratory distress syndrome in very prematur…
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CLINICAL_TRIALS trial_result · 2011-08-26Clinical Trial Update: Intrapleural Methylprednisolone Injection for Multiple Organ Failure With Acute Respiratory Distress Syndrome [Phase 2]
This Phase 2 clinical trial studied intrapleural methylprednisolone injection for patients with acute respiratory distress syndrome and mult…