Lung Injury
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-07-25Clinical Trial Update: Effect of Mechanical Ventilation on Plasma Concentration Level of R-spondin Proteins
A completed clinical trial investigated how mechanical ventilation affects plasma levels of R-spondin proteins in patients with Acute Lung I…
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CLINICAL_TRIALS trial_result · 2019-01-11Clinical Trial Update: Study of GSK2862277 in Subjects Undergoing Oesophagectomy Surgery [Phase 2]
Phase 2 study of GSK2862277 in adults undergoing oesophagectomy was terminated; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2018-10-22Clinical Trial Update: the Effect of Dopamine on Mechanical Ventilation Induced Lung Injury
Clinical trial evaluating the effect of dopamine on lung injury caused by mechanical ventilation; completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-13Clinical Trial Update: A Study to Investigate the Effects of Imatinib on Pulmonary Vascular Dysfunction in a Human Model of Lung Injury [Phase 1]
Phase 1 clinical trial evaluating the effects of imatinib on pulmonary vascular dysfunction in a human model of acute lung injury has been c…
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CLINICAL_TRIALS research · 2018-05-30Clinical Trial Update: The Effect of Using High-flow Nasal Oxygen-delivery System in Patients Under Intravenous General Anesthesia [NA]
Clinical trial update evaluating the effect of a high-flow nasal oxygen-delivery system in patients under intravenous general anesthesia. St…
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CLINICAL_TRIALS research · 2018-04-11Clinical Trial Update: Measurement of Lung Elastance and Transpulmonary Pressure Using Two Different Methods (Lungbarometry)
This clinical trial update discusses two methods for measuring lung elastance and transpulmonary pressure (Lungbarometry) in acute lung inju…
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CLINICAL_TRIALS trial_result · 2018-03-16Clinical Trial Update: CALIPSO: Calfactant for Acute Lung Injury in Pediatric Stem Cell Transplant and Oncology Patients [Phase 2, Phase 3]
Phase 2/Phase 3 trial evaluating Calfactant for acute lung injury in pediatric stem cell transplant and oncology patients has completed; res…
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CLINICAL_TRIALS trial_result · 2017-10-18Clinical Trial Update: SB-681323 IV for Subjects at Risk of Acute Lung Injury or ARDS [Phase 2]
Phase 2 trial evaluating intravenous SB-681323 in subjects at risk of acute lung injury or acute respiratory distress syndrome has completed…
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CLINICAL_TRIALS trial_result · 2017-09-28Clinical Trial Update: The Safety, Tolerability, PK and PD of GSK2586881 in Patients With Acute Lung Injury [Phase 2]
Phase 2 trial evaluating safety, tolerability, pharmacokinetics and pharmacodynamics of GSK2586881 in patients with acute lung injury; study…
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CLINICAL_TRIALS trial_result · 2017-09-13Clinical Trial Update: Ganciclovir/Valganciclovir for Prevention of CMV Reactivation in Acute Injury of the Lung and Respiratory Failure [Phase 2]
Phase 2 trial evaluating ganciclovir/valganciclovir for prevention of CMV reactivation in patients with acute lung injury and respiratory fa…
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CLINICAL_TRIALS trial_result · 2017-06-12Clinical Trial Update: A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of an Intravenous Infusion of GW328267X in Healthy Volunteers [Phase 1]
Phase 1 trial evaluating safety, tolerability, and pharmacokinetics/pharmacodynamics of intravenous GW328267X in healthy volunteers; the stu…
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CLINICAL_TRIALS trial_result · 2017-06-05Clinical Trial Update: Citrulline in Severe Sepsis [Phase 2]
A Phase 2 clinical trial evaluating citrulline in severe sepsis with acute lung injury has completed and posted results.
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CLINICAL_TRIALS trial_result · 2017-05-25Clinical Trial Update: Effects of Airway Conditioning Devices on Ventilator Associated Pneumonia:a Randomized Clinical Trial [NA]
This randomized clinical trial evaluates whether airway conditioning devices influence rates of ventilator-associated pneumonia in patients …
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CLINICAL_TRIALS trial_result · 2017-05-16Clinical Trial Update: IC14 Antibodies to Treat Individuals With Acute Lung Injury [Phase 2]
Phase 2 trial of IC14 antibodies for acute lung injury in adults was terminated.
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CLINICAL_TRIALS trial_result · 2017-05-15Clinical Trial Update: Airway Pressure Release Ventilation in Acute Lung Injury [NA]
This entry reports the termination of a clinical trial studying airway pressure release ventilation in patients with acute lung injury or ac…
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CLINICAL_TRIALS trial_result · 2017-05-03Clinical Trial Update: Effect of Variable PSV in Acute Lung Injury: Part I and Part II [NA]
Clinical trial evaluating the effects of variable pressure-support ventilation in patients with acute lung injury and acute respiratory dist…
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CLINICAL_TRIALS trial_result · 2017-04-28Clinical Trial Update: Comparative Evaluation of Albumin and Starch Effects in Acute Lung Injury (ALI) [Phase 3]
Phase 3 trial comparing albumin to starch therapy in acute lung injury and acute respiratory distress syndrome was terminated; results have …
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CLINICAL_TRIALS research · 2017-04-20Clinical Trial Update: Effects of Oxygen on Lung Tissue During Anesthesia
This clinical trial update describes a Vanderbilt University-sponsored study evaluating the effects of oxygen on lung tissue during anesthes…
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CLINICAL_TRIALS trial_result · 2017-03-03Clinical Trial Update: Limb RIPC in Patients Undergoing Lung Lobectomy. Study of Oxidative Lung Damage [NA]
A clinical trial investigating limb remote ischemic preconditioning to study oxidative lung damage in patients undergoing lung lobectomy has…
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CLINICAL_TRIALS trial_result · 2017-02-27Clinical Trial Update: Mechanical Ventilation, Directed by Esophageal Pressure Measurements, in Patients With Acute Lung Injury [NA]
This is a record of a completed clinical trial assessing mechanical ventilation guided by esophageal pressure measurements in patients with …
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CLINICAL_TRIALS research · 2017-02-23Clinical Trial Update: Remote Ischemic Preconditioning on Pulmonary Injury in Cardic Surgery [NA]
This clinical trial update examines remote ischemic preconditioning as a method to reduce pulmonary injury during cardiac surgery; the curre…
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CLINICAL_TRIALS trial_result · 2017-02-16Clinical Trial Update: Efficacy and Safety of a Lung Recruitment Protocol in Children With Acute Lung Injury [NA]
A completed clinical trial evaluating a lung recruitment protocol for acute lung injury in children, with results posted.
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CLINICAL_TRIALS research · 2017-02-09Clinical Trial Update: Measuring Energy Expenditure in ECMO (Extracorporeal Membrane Oxygenation) Patients
This document provides a status update on a clinical trial studying methods to measure energy expenditure in adult patients on ECMO, includi…
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CLINICAL_TRIALS withdrawal · 2017-01-30Clinical Trial Update: Role of Vascular Endothelial Growth Factor (VEGF) in Acute Lung Injury/Adult Respiratory Distress Syndrome (ARDS)
The VEGF-focused clinical trial in adult acute lung injury and acute respiratory distress syndrome has been withdrawn.
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CLINICAL_TRIALS trial_result · 2017-01-27Clinical Trial Update: Pharmacologic Impact on Sedation Assessments
This report provides an update on a clinical trial evaluating how pharmacologic factors influence sedation assessments in pediatric acute lu…