Lung Injury
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-01-11Clinical Trial Update: Study of GSK2862277 in Subjects Undergoing Oesophagectomy Surgery [Phase 2]
Phase 2 study of GSK2862277 in adults undergoing oesophagectomy was terminated; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2018-10-22Clinical Trial Update: the Effect of Dopamine on Mechanical Ventilation Induced Lung Injury
Clinical trial evaluating the effect of dopamine on lung injury caused by mechanical ventilation; completed with results posted in 2018.
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CLINICAL_TRIALS trial_result · 2018-07-13Clinical Trial Update: A Study to Investigate the Effects of Imatinib on Pulmonary Vascular Dysfunction in a Human Model of Lung Injury [Phase 1]
Phase 1 clinical trial evaluating the effects of imatinib on pulmonary vascular dysfunction in a human model of acute lung injury has been c…
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CLINICAL_TRIALS trial_result · 2018-03-16Clinical Trial Update: CALIPSO: Calfactant for Acute Lung Injury in Pediatric Stem Cell Transplant and Oncology Patients [Phase 2, Phase 3]
Phase 2/Phase 3 trial evaluating Calfactant for acute lung injury in pediatric stem cell transplant and oncology patients has completed; res…
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CLINICAL_TRIALS trial_result · 2017-10-18Clinical Trial Update: SB-681323 IV for Subjects at Risk of Acute Lung Injury or ARDS [Phase 2]
Phase 2 trial evaluating intravenous SB-681323 in subjects at risk of acute lung injury or acute respiratory distress syndrome has completed…
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CLINICAL_TRIALS trial_result · 2017-09-28Clinical Trial Update: The Safety, Tolerability, PK and PD of GSK2586881 in Patients With Acute Lung Injury [Phase 2]
Phase 2 trial evaluating safety, tolerability, pharmacokinetics and pharmacodynamics of GSK2586881 in patients with acute lung injury; study…
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CLINICAL_TRIALS trial_result · 2017-09-13Clinical Trial Update: Ganciclovir/Valganciclovir for Prevention of CMV Reactivation in Acute Injury of the Lung and Respiratory Failure [Phase 2]
Phase 2 trial evaluating ganciclovir/valganciclovir for prevention of CMV reactivation in patients with acute lung injury and respiratory fa…
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CLINICAL_TRIALS trial_result · 2017-06-12Clinical Trial Update: A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of an Intravenous Infusion of GW328267X in Healthy Volunteers [Phase 1]
Phase 1 trial evaluating safety, tolerability, and pharmacokinetics/pharmacodynamics of intravenous GW328267X in healthy volunteers; the stu…
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CLINICAL_TRIALS trial_result · 2017-06-05Clinical Trial Update: Citrulline in Severe Sepsis [Phase 2]
A Phase 2 clinical trial evaluating citrulline in severe sepsis with acute lung injury has completed and posted results.
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CLINICAL_TRIALS trial_result · 2017-05-25Clinical Trial Update: Effects of Airway Conditioning Devices on Ventilator Associated Pneumonia:a Randomized Clinical Trial [NA]
This randomized clinical trial evaluates whether airway conditioning devices influence rates of ventilator-associated pneumonia in patients …
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CLINICAL_TRIALS trial_result · 2017-05-16Clinical Trial Update: IC14 Antibodies to Treat Individuals With Acute Lung Injury [Phase 2]
Phase 2 trial of IC14 antibodies for acute lung injury in adults was terminated.
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CLINICAL_TRIALS trial_result · 2017-05-15Clinical Trial Update: Airway Pressure Release Ventilation in Acute Lung Injury [NA]
This entry reports the termination of a clinical trial studying airway pressure release ventilation in patients with acute lung injury or ac…
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CLINICAL_TRIALS trial_result · 2017-05-03Clinical Trial Update: Effect of Variable PSV in Acute Lung Injury: Part I and Part II [NA]
Clinical trial evaluating the effects of variable pressure-support ventilation in patients with acute lung injury and acute respiratory dist…
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CLINICAL_TRIALS trial_result · 2017-04-28Clinical Trial Update: Comparative Evaluation of Albumin and Starch Effects in Acute Lung Injury (ALI) [Phase 3]
Phase 3 trial comparing albumin to starch therapy in acute lung injury and acute respiratory distress syndrome was terminated; results have …
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CLINICAL_TRIALS trial_result · 2017-03-03Clinical Trial Update: Limb RIPC in Patients Undergoing Lung Lobectomy. Study of Oxidative Lung Damage [NA]
A clinical trial investigating limb remote ischemic preconditioning to study oxidative lung damage in patients undergoing lung lobectomy has…
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CLINICAL_TRIALS trial_result · 2017-02-27Clinical Trial Update: Mechanical Ventilation, Directed by Esophageal Pressure Measurements, in Patients With Acute Lung Injury [NA]
This is a record of a completed clinical trial assessing mechanical ventilation guided by esophageal pressure measurements in patients with …
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CLINICAL_TRIALS trial_result · 2017-02-16Clinical Trial Update: Efficacy and Safety of a Lung Recruitment Protocol in Children With Acute Lung Injury [NA]
A completed clinical trial evaluating a lung recruitment protocol for acute lung injury in children, with results posted.
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CLINICAL_TRIALS trial_result · 2017-01-27Clinical Trial Update: Pharmacologic Impact on Sedation Assessments
This report provides an update on a clinical trial evaluating how pharmacologic factors influence sedation assessments in pediatric acute lu…
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CLINICAL_TRIALS trial_result · 2016-12-19Clinical Trial Update: Biomarkers of Lung Injury With Low Tidal Volume Ventilation Compared With Airway Pressure Release Ventilation [NA]
This clinical trial update reports that the study comparing biomarkers of lung injury under low tidal volume ventilation versus airway press…
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CLINICAL_TRIALS trial_result · 2016-12-15Clinical Trial Update: The Role of Circulating Soluble CD74 in Acute Lung Injury
This completed clinical trial evaluated circulating soluble CD74 as a biomarker in patients with Acute Lung Injury and Acute Respiratory Dis…
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CLINICAL_TRIALS trial_result · 2016-11-23Clinical Trial Update: Intensive Alveolar Recruitment Protocol After Cardiac Surgery [NA]
This clinical trial update reports the results of using an intensive alveolar recruitment protocol after cardiac surgery to prevent ventilat…
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CLINICAL_TRIALS trial_result · 2016-10-11Clinical Trial Update: Clinical Effect of the Association of Noninvasive Ventilation and High Flow Nasal Oxygen Therapy in Resuscitation of Patients With Acute Lung Injury (FLORALI Study) [Phase 2, Phase 3]
The FLORALI trial update reports Phase 2/3 results evaluating noninvasive ventilation plus high-flow nasal oxygen therapy in resuscitating p…
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CLINICAL_TRIALS trial_result · 2016-04-13Clinical Trial Update: Early Versus Delayed Enteral Feeding to Treat People With Acute Lung Injury or Acute Respiratory Distress Syndrome (The EDEN Study) [Phase 3]
The EDEN Study reports the completion of a Phase 3 trial comparing early versus delayed enteral feeding in adults with acute lung injury or …
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CLINICAL_TRIALS trial_result · 2016-04-13Clinical Trial Update: Early Versus Delayed Enteral Feeding and Omega-3 Fatty Acid/Antioxidant Supplementation for Treating People With Acute Lung Injury or Acute Respiratory Distress Syndrome (The EDEN-Omega Study) [Phase 3]
This Phase 3 clinical trial update reports termination of the EDEN-Omega study evaluating early versus delayed enteral feeding with omega-3 …
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CLINICAL_TRIALS trial_result · 2016-01-28Clinical Trial Update: Biological Markers to Identify Early Sepsis and Acute Lung Injury
The clinical trial update reports the completion of a study investigating biological markers to identify early sepsis and acute lung injury.