Kidney Injury
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2011-06-23Clinical Trial Update: Angiotensin in Septic Kidney Injury Trial [Phase 2]
Phase 2 clinical trial evaluating angiotensin for septic kidney injury is ongoing, with current status not provided.
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CLINICAL_TRIALS research · 2011-05-27Clinical Trial Update: Metabolic Aspects of Citrate Anticoagulation in Renal Replacement Therapy
This clinical trial update discusses the metabolic aspects of citrate-based anticoagulation during renal replacement therapy in critically i…
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CLINICAL_TRIALS trial_result · 2011-05-25Clinical Trial Update: Clinical Trial Comparing Continuous Versus Intermittent Hemodialysis in ICU Patients [Phase 2, Phase 3]
This document notes the completion of a Phase 2/3 clinical trial comparing continuous versus intermittent hemodialysis in ICU patients with …
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CLINICAL_TRIALS research · 2011-05-25Clinical Trial Update: N-acetylcysteine to Prevent Renal Failure [NA]
A clinical trial evaluating whether N-acetylcysteine can prevent acute kidney injury under oxidative stress conditions; current status is no…
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CLINICAL_TRIALS trial_result · 2011-05-10Clinical Trial Update: Prevention of Contrast-Induced Nephropathy [NA]
This entry notes the completed clinical trial evaluating prevention of contrast-induced nephropathy sponsored by the University of Alberta.
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CLINICAL_TRIALS trial_result · 2011-04-20Clinical Trial Update: N-Acetylcysteine for Preventing Renal Injury After Cardiac Surgery [Phase 3]
A Phase 3 trial evaluating N-Acetylcysteine to prevent renal injury after cardiac surgery has completed.
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CLINICAL_TRIALS trial_result · 2011-02-23Clinical Trial Update: A Dose Escalation and Safety Study of I5NP in Patients Undergoing Major Cardiovascular Surgery [Phase 1]
A Phase 1 dose-escalation safety study of I5NP in patients undergoing major cardiovascular surgery, sponsored by Quark Pharmaceuticals; the …
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CLINICAL_TRIALS trial_result · 2011-01-24Clinical Trial Update: Neutrophil Gelatinase-associated Lipocalin (NGAL) Evaluation in Emergency Department (ED) All-Comers
A completed trial evaluating NGAL as a biomarker for acute kidney injury in emergency department all-comers. The study status is completed.
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CLINICAL_TRIALS trial_result · 2010-12-01Clinical Trial Update: Bicarbonate v Saline to Prevent Contrast Nephropathy [Phase 4]
Phase 4 trial comparing bicarbonate versus saline to prevent contrast-induced nephropathy was terminated.
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CLINICAL_TRIALS trial_result · 2010-11-16Clinical Trial Update: A Dose Escalation and Safety Study of I5NP to Prevent Acute Kidney Injury (AKI) in Patients at High Risk of AKI Undergoing Major Cardiovascular Surgery (QRK.004) [Phase 1]
Phase 1 dose-escalation and safety trial of I5NP to prevent acute kidney injury in high-risk cardiovascular surgery patients has been termin…
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CLINICAL_TRIALS trial_result · 2010-11-02Clinical Trial Update: Clinical Study to Investigate the Safety and Pharmacokinetics of Udenafil Tablet in Renal Impaired Male Patients [Phase 1]
A Phase 1 study evaluating the safety and pharmacokinetics of udenafil in male patients with renal impairment has been completed.
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CLINICAL_TRIALS trial_result · 2010-10-26Clinical Trial Update: Comparison of Slow Efficiency Daily Dialysis (SLEDD) With Unfractionated Heparin Versus Citrasate in Critically Ill Patients. [Phase 4]
Phase 4 trial comparing Slow Efficiency Daily Dialysis (SLEDD) using unfractionated heparin versus Citrasate in critically ill patients with…
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CLINICAL_TRIALS research · 2010-07-12Clinical Trial Update: The Acetylcysteine for Contrast-Induced Nephropathy Trial [Phase 3]
This update reports on a Phase 3 trial evaluating acetylcysteine to prevent contrast-induced nephropathy in patients at risk for acute kidne…
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CLINICAL_TRIALS trial_result · 2010-06-28Clinical Trial Update: Referral Patterns for Hospital Acquired Acute Kidney Injury and Relevance to Renal Outcomes
This completed study evaluated referral patterns for hospital-acquired acute kidney injury and their relationship to renal outcomes.
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CLINICAL_TRIALS trial_result · 2010-05-31Clinical Trial Update: Neutrophile Gelatinase Associated Lipocalin Evaluation in Septic Acute Kidney Injury
A clinical trial update examining neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker in septic acute kidney injury.
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CLINICAL_TRIALS trial_result · 2010-03-12Clinical Trial Update: High Dose CVVHDF Compared to Standard Dose CVVHDF [Phase 3]
This Phase 3 trial compares high-dose CVVHDF to standard-dose CVVHDF in acute kidney injury and has completed with results posted.
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CLINICAL_TRIALS trial_result · 2010-03-05Clinical Trial Update: PROVOCATION Trial - PROphylactic intraVenOus Hydration for Contrast Agent Toxicity PreventION [Phase 2, Phase 3]
The PROVOCATION trial studied prophylactic intravenous hydration to prevent contrast-induced kidney injury and has completed Phase 2 and Pha…
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CLINICAL_TRIALS trial_result · 2010-02-25Clinical Trial Update: Prevention of Contrast Nephropathy by Sodium Bicarbonate Versus Sodium Chloride and N-acetylcysteine [NA]
Clinical trial comparing sodium bicarbonate to sodium chloride and N-acetylcysteine for preventing contrast-induced nephropathy has complete…
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CLINICAL_TRIALS trial_result · 2010-02-10Clinical Trial Update: Efficacy of Erythropoietin to Prevent Acute Kidney Injury in Chronic Kidney Disease Patients Undergoing Cardiac Surgery [Phase 3]
Phase 3 trial evaluating whether erythropoietin can prevent acute kidney injury in patients with chronic kidney disease undergoing cardiac s…
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CLINICAL_TRIALS research · 2010-02-02Clinical Trial Update: Study of Heat Shock Proteins as Prognostic Factor of Acute Renal Failure in Children (HSP-Study)
A clinical trial investigating whether heat shock proteins can serve as a prognostic factor for acute kidney failure in children. The curren…
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CLINICAL_TRIALS trial_result · 2010-01-29Clinical Trial Update: Analysis of Clinical Outcomes in Patients Undergoing Acute Dialysis Therapy at Intensive Care Units
A clinical trial update analyzes clinical outcomes for patients with acute kidney injury undergoing dialysis in intensive care units.
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CLINICAL_TRIALS trial_result · 2009-12-02Clinical Trial Update: Effect of Remote Ischemic Preconditioning on Acute Kidney Injury in Patients Undergoing Heart Valve Replacement Surgery With Cardiopulmonary Bypass [NA]
A completed clinical study assessing whether remote ischemic preconditioning reduces acute kidney injury in patients undergoing heart valve …
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CLINICAL_TRIALS research · 2009-12-01Clinical Trial Update: Study of the Causes of the Breakdown of Muscle Fibers in Hospitalized Patients
This clinical trial update describes a study investigating the causes of muscle fiber breakdown (rhabdomyolysis) and related myopathies in h…
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CLINICAL_TRIALS trial_result · 2009-10-23Clinical Trial Update: Dosing Vancomycin in Patients on Sustained Low Efficiency Daily Hemodiafiltration (SLEDD-f)
A clinical trial update detailing vancomycin dosing for patients with acute kidney injury on sustained low-efficiency daily hemodiafiltratio…
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CLINICAL_TRIALS trial_result · 2009-09-23Clinical Trial Update: BNP (Nesiritide) vs. Placebo to Protect Kidney Function in Patients Undergoing Heart Bypass Surgery. [Phase 1, Phase 2]
A completed Phase 1/2 trial comparing nesiritide (BNP) to placebo to protect kidney function in patients undergoing heart bypass surgery.