Kidney Injury
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2014-02-25Clinical Trial Update: Indoxyl Sulfate Induces Leukocyte-endothelial Interactions Through Up-regulation of ICAM-1 in Acute Kidney Injury
A clinical trial update describing how indoxyl sulfate may promote leukocyte-endothelial interactions by upregulating ICAM-1 in acute kidney…
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CLINICAL_TRIALS research · 2014-02-10Clinical Trial Update: Sensitivity and Specificity of NGAL in an Emergency Room Population
A completed clinical trial evaluated the sensitivity and specificity of the NGAL biomarker for detecting acute kidney injury in an emergency…
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CLINICAL_TRIALS research · 2014-02-04Clinical Trial Update: Preconditioning Against Renal Damage Under Contrast Examination [NA]
This entry notes a clinical trial from Ireland investigating preconditioning to prevent renal injury during contrast-enhanced examination. T…
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CLINICAL_TRIALS safety_alert · 2014-01-28Clinical Trial Update: Adverse Reactions to MR and CT-examinations (Enhanced and Unenhanced)
Clinical trial update reporting adverse reactions observed during MR and CT imaging with and without contrast, including contrast-induced ne…
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CLINICAL_TRIALS trial_result · 2014-01-23Clinical Trial Update: Pharmacokinetic Study of 48-hour Sevoflurane Inhalation Using a Disposable Delivery System (AnaConDa©) in ICU Patients With Acute Kidney Injury [Phase 2]
This Phase 2 clinical trial evaluates the pharmacokinetics of a 48-hour sevoflurane inhalation delivered via the AnaConDa disposable system …
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CLINICAL_TRIALS trial_result · 2014-01-15Clinical Trial Update: Renal Resistive Index and Cardiac Output Changes During Resuscitation Predict the Occurrence of Acute Kidney Injury in Septic Shock Patients
The clinical trial investigates if renal resistive index and cardiac output changes during resuscitation can predict acute kidney injury in …
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CLINICAL_TRIALS research · 2014-01-15Clinical Trial Update: Effects of AN69 ST Hemofilter on Coagulation During Continuous Renal Replacement Therapy in Critically Ill [NA]
This clinical trial update evaluates the effects of the AN69 ST Hemofilter on coagulation during continuous renal replacement therapy in cri…
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CLINICAL_TRIALS trial_result · 2013-12-25Clinical Trial Update: Incidence, Risk Factors, and Risk Model of Acute Kidney Injury After Thoracic Aortic Surgery
A completed clinical trial from Samsung Medical Center reports on the incidence and risk factors of acute kidney injury after thoracic aorti…
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CLINICAL_TRIALS trial_result · 2013-12-25Clinical Trial Update: Accuracy of Pre-existing Risk Scoring Models for Predicting Acute Kidney Injury in Patients Who Underwent Aortic Surgery Using a Gray Zone Approach
This clinical trial update evaluates how accurately pre-existing risk scoring models predict postoperative acute kidney injury in patients u…
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CLINICAL_TRIALS research · 2013-11-19Clinical Trial Update: Plasma Neutrophil Gelatinase-associated Lipocalin (NGAL) as Early Biomarker for Renal Dysfunction and Good Neurologic Outcome in Out of Hospital Cardiac Arrest Patients
This clinical trial update discusses evaluating plasma neutrophil gelatinase-associated lipocalin (NGAL) as an early biomarker for renal dys…
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CLINICAL_TRIALS trial_result · 2013-11-08Clinical Trial Update: Short-Term Alpha Lipoic Acid Therapy for Prevention of Contrast-induced Acute Kidney Injury and Endothelial Dysfunction in Type 2 Diabetes [Phase 4]
A Phase 4 clinical trial update investigates short-term alpha-lipoic acid to prevent contrast-induced acute kidney injury and endothelial dy…
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CLINICAL_TRIALS trial_result · 2013-10-14Clinical Trial Update: Early Versus Late Renal Replacement Therapy After Cardiac Surgery [NA]
Completed clinical trial comparing early versus late renal replacement therapy initiation in patients with acute kidney injury following car…
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CLINICAL_TRIALS trial_result · 2013-09-18Clinical Trial Update: Seattle Cardiorenal Remote Ischemic Preconditioning Trial [NA]
This clinical trial update reports that the Seattle Cardiorenal Remote Ischemic Preconditioning Trial (NCT01260259) has completed, involving…
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CLINICAL_TRIALS trial_result · 2013-09-11Clinical Trial Update: Thymoglobulin in Cadaver Donor [Phase 2]
Phase 2 study evaluating Thymoglobulin to prevent kidney injury in brain-dead donors has completed. Trial results are not provided in the sn…
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CLINICAL_TRIALS trial_result · 2013-08-30Clinical Trial Update: Acute Kidney Injury in Septic Critically Ill Patients : Are Aminoglycosides Really Harmful?
A completed clinical trial investigated whether aminoglycoside antibiotics worsen acute kidney injury in septic, critically ill patients.
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CLINICAL_TRIALS trial_result · 2013-08-26Clinical Trial Update: Dexamethasone and Chemotherapy With or Without Plasma Exchange in Patients With Newly Diagnosed Multiple Myeloma and Acute Kidney Failure [Phase 3]
Phase 3 trial comparing dexamethasone-based chemotherapy with or without plasma exchange in newly diagnosed multiple myeloma with acute kidn…
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CLINICAL_TRIALS trial_result · 2013-08-19Clinical Trial Update: Analysis of Remote-ischemic Preconditioning Effects on Kidney Function
A completed clinical trial analyzes whether remote-ischemic preconditioning affects kidney function. The sponsor listed is the University of…
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CLINICAL_TRIALS trial_result · 2013-08-16Clinical Trial Update: Acute Renal Failure Trial Network (ATN) Study [Phase 3]
Results from the Phase 3 Acute Renal Failure Trial Network (ATN) study have been posted. The trial investigated management strategies for ac…
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CLINICAL_TRIALS research · 2013-08-07Clinical Trial Update: MIOX for Early Detection of Acute Kidney Injury After Cardiac Surgery
Clinical trial assessing the use of MIOX as a biomarker for early detection of acute kidney injury after cardiac surgery.
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CLINICAL_TRIALS trial_result · 2013-07-25Clinical Trial Update: Safety and Efficiency Study of Loading Dose Atorvastatin in Cardiac Surgery [NA]
A completed clinical trial evaluated a loading dose of atorvastatin in cardiac surgery to assess safety and potential protection against acu…
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CLINICAL_TRIALS trial_result · 2013-07-08Clinical Trial Update: Effect of Red Wine, White Wine and Beer on Contrast-Medium Induced Acute Kidney Injury [Phase 3]
Phase 3 clinical trial from University of Cologne evaluating whether red wine, white wine, or beer influences contrast-medium induced acute …
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CLINICAL_TRIALS trial_result · 2013-06-25Clinical Trial Update: The Effects of Dexmedetomidine on Postoperative Renal Function in Valvular Heart Surgery [Phase 4]
A Phase 4 clinical trial examining whether dexmedetomidine affects postoperative renal function and the incidence of acute kidney injury aft…
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CLINICAL_TRIALS research · 2013-06-12Clinical Trial Update: The Diagnostic Role of Cystein-rich Protein 61 (Cyr61) in Acute Kidney Injury: Correlation With the Harmonic Analysis of Arterial Pressure Pulse Waves.
A clinical trial studying whether cystein-rich protein 61 (Cyr61) can diagnose acute kidney injury in adults undergoing elective cardiac sur…
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CLINICAL_TRIALS trial_result · 2013-05-23Clinical Trial Update: NGAL, an Early Predictive Marker of Acute Kidney Injury After Cardiac Surgery in Neonates and Infants
This clinical trial update reports NGAL as an early predictive biomarker for acute kidney injury following cardiac surgery in neonates and i…
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CLINICAL_TRIALS research · 2013-05-17Clinical Trial Update: Specimen Stability Study
This clinical trial update reports the status of a specimen stability study related to acute kidney injury. The study has been completed.