Kidney Injury
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-08-01Clinical Trial Update: Bicarbonate in Cardiac Surgery [Phase 2]
A Phase 2 clinical trial evaluating bicarbonate for acute kidney injury in cardiac surgery has been terminated.
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CLINICAL_TRIALS trial_result · 2012-06-28Clinical Trial Update: Fenoldopam in Pediatric Cardiac Surgery [Phase 3]
Phase 3 trial evaluating fenoldopam for pediatric cardiac surgery has completed; sponsor information and acute kidney injury context are not…
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CLINICAL_TRIALS trial_result · 2012-06-20Clinical Trial Update: N-acetylcysteine Protects From Aminoglycosides Induced Nephrotoxicity [Phase 2, Phase 3]
Phase 2 and Phase 3 trials evaluated whether N-acetylcysteine can prevent aminoglycoside-related kidney injury; the studies have been comple…
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CLINICAL_TRIALS trial_result · 2012-06-08Clinical Trial Update: Prevention of Contrast Induced Nephropathy (NIC) by Intravenous Versus Oral Rehydration [NA]
A completed clinical trial comparing intravenous versus oral rehydration for prevention of contrast-induced nephropathy in patients with acu…
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CLINICAL_TRIALS trial_result · 2012-06-05Clinical Trial Update: Intravenous High Dose NAC and Sodium Bicarbonate for the Prevention of Contrast-induced Acute Injury [NA]
A completed clinical trial evaluated intravenous high-dose N-acetylcysteine plus sodium bicarbonate for the prevention of contrast-induced a…
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CLINICAL_TRIALS trial_result · 2012-05-08Clinical Trial Update: Urine and Serum Biomarkers for Early Detection of Acute Kidney Injury
This clinical trial update reports the completion of a study evaluating urine and serum biomarkers for the early detection of acute kidney i…
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CLINICAL_TRIALS trial_result · 2012-03-15Clinical Trial Update: An Trial of Two Dosing Regimens of AP214 for the Prevention of Kidney Injury in Patients Undergoing Cardiac Surgery [Phase 2]
Completion of a Phase 2 trial evaluating two dosing regimens of AP214 to prevent kidney injury in patients undergoing cardiac surgery.
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CLINICAL_TRIALS trial_result · 2012-03-14Clinical Trial Update: Effect of Vitamin E+Selenium on Kidney Function in Controlled Hypotension [Phase 2]
A Phase 2 clinical trial from Tehran University of Medical Sciences is examining whether vitamin E plus selenium can improve kidney function…
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CLINICAL_TRIALS trial_result · 2012-03-12Clinical Trial Update: The Optimal Mode of Renal Replacement Therapy in Acute Kidney Injury (OMAKI) Study [Phase 4]
The OMAKI study evaluated the optimal mode of renal replacement therapy in acute kidney injury and has completed its Phase 4 trial.
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CLINICAL_TRIALS trial_result · 2012-02-27Clinical Trial Update: Achieving Medication Safety During Acute Kidney Injury [NA]
A Vanderbilt University study focused on improving medication safety in patients with acute kidney injury has completed, with results posted…
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CLINICAL_TRIALS trial_result · 2012-01-31Clinical Trial Update: Study Comparing High Cut-off Haemofiltration With Standard Haemofiltration in Acute Renal Failure [Phase 1, Phase 2]
A Phase 1/2 clinical trial comparing high cut-off haemofiltration with standard haemofiltration in acute kidney injury has been completed.
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CLINICAL_TRIALS trial_result · 2012-01-06Clinical Trial Update: Extracardiac Complications After Cardiac Surgery
A completed clinical trial from the University of Turin assessing extracardiac complications after cardiac surgery, including Acute Lung Inj…
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CLINICAL_TRIALS trial_result · 2011-09-21Clinical Trial Update: Fluid Balance and Clinical Outcomes
This update reports on a completed clinical trial evaluating fluid balance and input/output and how these factors relate to clinical outcome…
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CLINICAL_TRIALS trial_result · 2011-08-03Clinical Trial Update: The Application of Soluble Triggering Receptor Expressed on Myeloid Cells-1 in Sepsis & Relevant Acute Kidney Injuries
A completed clinical trial investigating soluble TREM-1 in sepsis and related acute kidney injury conditions; no results are described in th…
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CLINICAL_TRIALS trial_result · 2011-07-04Clinical Trial Update: Prevention of Perioperative Acute Renal Failure [Phase 4]
A Phase 4 trial evaluating prevention of perioperative acute kidney injury in patients undergoing abdominal surgery was terminated.
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CLINICAL_TRIALS trial_result · 2011-06-28Clinical Trial Update: Cystatin C as a Marker for Detecting Early Renal Dysfunction in a Pediatric Emergency Department
A pediatric emergency department trial evaluated cystatin C as an early marker of renal dysfunction; the study has completed.
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CLINICAL_TRIALS trial_result · 2011-05-25Clinical Trial Update: Clinical Trial Comparing Continuous Versus Intermittent Hemodialysis in ICU Patients [Phase 2, Phase 3]
This document notes the completion of a Phase 2/3 clinical trial comparing continuous versus intermittent hemodialysis in ICU patients with …
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CLINICAL_TRIALS trial_result · 2011-05-10Clinical Trial Update: Prevention of Contrast-Induced Nephropathy [NA]
This entry notes the completed clinical trial evaluating prevention of contrast-induced nephropathy sponsored by the University of Alberta.
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CLINICAL_TRIALS trial_result · 2011-04-20Clinical Trial Update: N-Acetylcysteine for Preventing Renal Injury After Cardiac Surgery [Phase 3]
A Phase 3 trial evaluating N-Acetylcysteine to prevent renal injury after cardiac surgery has completed.
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CLINICAL_TRIALS trial_result · 2011-02-23Clinical Trial Update: A Dose Escalation and Safety Study of I5NP in Patients Undergoing Major Cardiovascular Surgery [Phase 1]
A Phase 1 dose-escalation safety study of I5NP in patients undergoing major cardiovascular surgery, sponsored by Quark Pharmaceuticals; the …
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CLINICAL_TRIALS trial_result · 2011-01-24Clinical Trial Update: Neutrophil Gelatinase-associated Lipocalin (NGAL) Evaluation in Emergency Department (ED) All-Comers
A completed trial evaluating NGAL as a biomarker for acute kidney injury in emergency department all-comers. The study status is completed.
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CLINICAL_TRIALS trial_result · 2010-12-01Clinical Trial Update: Bicarbonate v Saline to Prevent Contrast Nephropathy [Phase 4]
Phase 4 trial comparing bicarbonate versus saline to prevent contrast-induced nephropathy was terminated.
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CLINICAL_TRIALS trial_result · 2010-11-16Clinical Trial Update: A Dose Escalation and Safety Study of I5NP to Prevent Acute Kidney Injury (AKI) in Patients at High Risk of AKI Undergoing Major Cardiovascular Surgery (QRK.004) [Phase 1]
Phase 1 dose-escalation and safety trial of I5NP to prevent acute kidney injury in high-risk cardiovascular surgery patients has been termin…
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CLINICAL_TRIALS trial_result · 2010-11-02Clinical Trial Update: Clinical Study to Investigate the Safety and Pharmacokinetics of Udenafil Tablet in Renal Impaired Male Patients [Phase 1]
A Phase 1 study evaluating the safety and pharmacokinetics of udenafil in male patients with renal impairment has been completed.
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CLINICAL_TRIALS trial_result · 2010-10-26Clinical Trial Update: Comparison of Slow Efficiency Daily Dialysis (SLEDD) With Unfractionated Heparin Versus Citrasate in Critically Ill Patients. [Phase 4]
Phase 4 trial comparing Slow Efficiency Daily Dialysis (SLEDD) using unfractionated heparin versus Citrasate in critically ill patients with…