Kidney Injury
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CLINICAL_TRIALS research · 2025-09-08Clinical Trial Update: Clinical Study to Evaluate the Efficacy and Safety of Mesenchymal Stromal Cells (Amimestrocel ) in Patients With Acute Kidney Injury [Phase 2]
Phase 2 clinical trial evaluating the efficacy and safety of Amimestrocel (mesenchymal stromal cells) in patients with acute kidney injury i…
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CLINICAL_TRIALS research · 2025-09-05Clinical Trial Update: Impact of Intraoperative Blood Pressure Components on Postoperative AKI: A Phenotype-Stratified Analysis
A clinical trial update describing a phenotype-stratified analysis of how intraoperative blood pressure components relate to postoperative a…
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CLINICAL_TRIALS research · 2025-09-04Clinical Trial Update: A Patient-centered Trial of a Process-of-care Intervention in Hospitalized AKI Patients: the COPE-AKI Trial [NA]
A patient-centered process-of-care intervention trial in hospitalized acute kidney injury patients (COPE-AKI) is currently recruiting.
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Genetic Determinants of Kidney Disease in People of African Ancestry With HIV
This clinical trial entry describes an ACTIVE_NOT_RECRUITING study investigating genetic determinants of HIV-associated kidney disease in pe…
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CLINICAL_TRIALS research · 2025-09-03Clinical Trial Update: Timing of Renal Replacement Therapy in the Critically Ill Patients
A ClinicalTrials.gov study is investigating the timing of renal replacement therapy in critically ill patients with acute kidney injury and …
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CLINICAL_TRIALS research · 2025-09-02Clinical Trial Update: Shared Decision-Making for Families in Critical Dialysis Initiation [NA]
This entry describes a clinical trial examining shared decision-making for families during critical dialysis initiation in acute kidney inju…
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CLINICAL_TRIALS research · 2025-08-26Clinical Trial Update: Renal Oximetry-Guided Anesthesia With Near-Infrared Spectroscopy for Improved Postoperative Outcomes [Phase 1]
Phase 1 clinical trial evaluating renal oximetry-guided anesthesia using near-infrared spectroscopy to improve postoperative outcomes in acu…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: Does High-dose Vitamin B3 Supplementation Prevent Major Adverse Kidney Events During Septic Shock? [Phase 3]
This update describes a Phase 3 trial assessing whether high-dose nicotinamide (Vitamin B3) can prevent major adverse kidney events in septi…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Risk Factors of Postoperative Acute Kidney Injury and Mortality Among Hospitalized Patients Undergoing Major Surgery
Clinical trial update on risk factors for postoperative acute kidney injury and mortality among hospitalized patients undergoing major surge…
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Risk of Acute Kidney Injury in Pulmonary Endarterectomy
A clinical trial evaluating the risk of acute kidney injury in patients undergoing pulmonary endarterectomy; the study has not yet started r…
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CLINICAL_TRIALS research · 2025-08-20Clinical Trial Update: The Efficacy of Intravenous Amino Acids in Reducing the Occurrence of AKI After Live Donor Liver Transplant [NA]
This clinical trial investigates whether intravenous amino acids can reduce acute kidney injury after a live donor liver transplant, and the…
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CLINICAL_TRIALS research · 2025-08-20Clinical Trial Update: Venous Excess and Lung Ultrasound During Continuous Kidney Replacement Therapy in Critically Ill Patients
An update on a study evaluating venous excess and lung ultrasound during continuous kidney replacement therapy in critically ill patients.
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: Cardiopulmonary Bypass Induced Red Blood Cell Lysis
A clinical trial is currently recruiting to study cardiopulmonary bypass–induced red blood cell lysis during cardiac surgery and its associa…
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: The Effects of Empagliflozin on Renal Outcomes in Post Severe Acute Kidney Injury Survivors [Phase 1]
Phase 1 trial evaluating empagliflozin for renal outcomes in survivors of severe acute kidney injury. The study is currently active but not …
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: A Comparison of Renal vs Limb NIRS for Predicting Cardiac Surgery Associated Acute Kidney Injury
This clinical trial update shows that a study comparing renal vs limb near-infrared spectroscopy (NIRS) to predict cardiac surgery-associate…
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: Study on the Establishment of a System for Early Warning and Prognostic Evaluation of Patients With Heat Stroke
A clinical trial protocol to establish a system for early warning and prognostic evaluation in heat stroke patients; the study is not yet re…
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: French AKI Registry (FAKIR): A Multicenter Study on the In-Hospital Management and Outcomes of Severe Acute Kidney Injury in Nephrology Units
A multicenter French registry study (FAKIR) on in-hospital management and outcomes of severe acute kidney injury in nephrology units; status…
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: Safety & Efficacy of RenalGuard® Therapy in the Prevention of Cardiac Surgery Associated Acute Kidney Injury [NA]
This clinical trial update concerns the planned safety and efficacy evaluation of RenalGuard Therapy to prevent cardiac surgery-associated a…
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CLINICAL_TRIALS research · 2025-08-13Clinical Trial Update: Biorepository to Support Research in Kidney Diseases
A Yale University biorepository for kidney disease research is currently enrolling by invitation, focusing on conditions such as Acute Kidne…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: Effects of Different Continuous Renal Replacement Therapy Patterns on Ionized Calcium in Patients With Citrate Anticoagulants Using Calcium-containing Replacement Solutions
A clinical trial assessing how different continuous renal replacement therapy patterns affect ionized calcium in patients on regional citrat…
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CLINICAL_TRIALS research · 2025-08-03Clinical Trial Update: Dementia and Kidney Disease: Epidemiological Approaches to Risk Factors and Treatment Strategies
Karolinska Institutet is conducting an active-not-recruiting study using epidemiological methods to examine risk factors and treatment strat…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: Intravenous vs. Oral Hydration to Reduce the Risk of Post-Contrast Acute Kidney Injury After Intravenous Contrast-Enhanced Computed Tomography in Patients With Severe Chronic Kidney Disease [NA]
A recruiting clinical trial compares intravenous saline hydration with oral hydration to reduce the risk of post-contrast acute kidney injur…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: The Effects of Dexmedetomidine and Remifentanil on Kidney Injury After Muscle Compression Injury in Rats [NA]
A completed preclinical study in rats evaluated whether dexmedetomidine and remifentanil influence kidney injury after muscle compression. T…
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CLINICAL_TRIALS research · 2025-07-30Clinical Trial Update: Targeted Blood-pressure Management and Acute Kidney Injury After Coronary Artery Bypass Surgery [NA]
A clinical study evaluating targeted blood-pressure management to reduce acute kidney injury after off-pump coronary artery bypass surgery; …
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CLINICAL_TRIALS research · 2025-07-29Clinical Trial Update: Acute Kidney Injury Genomics and Biomarkers in TAVR Study
Clinical trial update on genomics and biomarkers for acute kidney injury in patients undergoing transcatheter aortic valve replacement (TAVR…