Acromegaly
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-02-15Clinical Trial Update: Single Dose Pharmacology Study of DG3173 and Octreotide in Acromegalic Patients. [Phase 2]
Phase 2 single-dose pharmacology study of DG3173 and octreotide in acromegaly completed with posted results.
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CLINICAL_TRIALS trial_result · 2017-12-15Clinical Trial Update: Phase II Study of Subcutaneous Inj. Depot of Octreotide in Patients With Acromegaly and Neuroendocrine Tumours (NETs) [Phase 2]
Phase II study of a subcutaneous depot formulation of octreotide in acromegaly and neuroendocrine tumors has completed with posted results.
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CLINICAL_TRIALS trial_result · 2017-10-13Clinical Trial Update: A Pilot Study of Rosiglitazone in the Treatment of GH Secreting Pituitary Adenomas [NA]
This entry reports a pilot study of rosiglitazone for GH-secreting pituitary adenomas. It provides limited information, with the trial statu…
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: Tissue Biomarker for Pegvisomant Action [NA]
A completed trial update investigating tissue biomarkers related to Pegvisomant action in acromegaly; results have been posted.
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CLINICAL_TRIALS trial_result · 2017-05-03Clinical Trial Update: Pituitary Histopathology and Hyperprolactinaemia and Risk of Glucose Metabolic Disturbances in Acromegaly.
An update on a clinical trial evaluating pituitary histopathology and hyperprolactinaemia and their association with glucose metabolic distu…
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CLINICAL_TRIALS trial_result · 2017-03-06Clinical Trial Update: Efficacy of Octreotide Acetate and Cabergoline in Patients With Acromegaly [Phase 4]
A Phase 4 trial by Novartis evaluated the efficacy of combining octreotide acetate with cabergoline in patients with acromegaly, and the stu…
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CLINICAL_TRIALS trial_result · 2017-02-24Clinical Trial Update: Octreotide Efficacy and Safety in First-line Acromegalic Patients [Phase 4]
Phase 4 trial results evaluate octreotide as first-line therapy for acromegaly, reporting its efficacy and safety outcomes.
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CLINICAL_TRIALS trial_result · 2017-01-26Clinical Trial Update: Treatment of Acromegaly With Somatostatin Analogs: GH vs. IGF-I as Primary Biochemical Target [Phase 4]
A completed Phase 4 trial evaluating somatostatin analog therapy for acromegaly. The study compared GH versus IGF-I as the primary biochemic…
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CLINICAL_TRIALS trial_result · 2016-11-07Clinical Trial Update: Study Comparing SOM230 Subcutaneously and Sandostatin Subcutaneously in Acromegalic Patients [Phase 2]
A Phase 2 trial comparing subcutaneous pasireotide (SOM230) with subcutaneous octreotide (Sandostatin) in adults with acromegaly has complet…
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CLINICAL_TRIALS trial_result · 2016-08-03Clinical Trial Update: Pasireotide LAR and Pegvisomant Study in Acromegaly [Phase 4]
Phase 4 trial update from Erasmus Medical Center evaluating Pasireotide LAR in combination with Pegvisomant for acromegaly; the current stat…
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CLINICAL_TRIALS trial_result · 2016-06-16Clinical Trial Update: Phase II Study With ITF2984 in Acromegalic Patients [Phase 2]
Phase II trial of ITF2984 in acromegaly has completed; no efficacy results are provided in the available summary.
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CLINICAL_TRIALS trial_result · 2016-02-10Clinical Trial Update: Study to Assess the Efficacy and Safety of Repeated Administration of BIM 23A760 in Patients With Acromegaly [Phase 2]
A Phase 2 clinical trial evaluating repeated administration of BIM 23A760 in acromegaly was terminated with results posted in 2016.
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CLINICAL_TRIALS trial_result · 2015-12-14Clinical Trial Update: Study to Assess the Efficacy of an Extended Injection Interval Schedule of Lanreotide Autogel in Acromegalic Subjects [Phase 4]
A Phase 4 study assessing the efficacy of an extended injection interval schedule of lanreotide Autogel in people with acromegaly, with resu…
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CLINICAL_TRIALS trial_result · 2015-12-03Clinical Trial Update: Surgical Versus Medical Treatment of Acromegaly
A completed clinical trial conducted under University of Aarhus evaluating surgical versus medical treatment for acromegaly.
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CLINICAL_TRIALS trial_result · 2015-12-01Clinical Trial Update: Efficacy and Safety of Octreotide (MYCAPSSA™ [Formerly Octreolin™]) for Acromegaly [Phase 3]
Phase 3 trial results evaluate the efficacy and safety of MYCAPSSA (octreotide) for treating acromegaly. The study completed with results po…
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CLINICAL_TRIALS trial_result · 2015-04-28Clinical Trial Update: Hormonal Outcomes in Acromegalic Patients With Treated Surgery With or Without Long Acting Somatostatin Analogues [Phase 4]
This Clinical Trial Update reports on hormonal outcomes in acromegaly patients who have undergone surgery, with or without long-acting somat…
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CLINICAL_TRIALS trial_result · 2015-03-18Clinical Trial Update: Effect of Growth Hormone (GH) on Cardiac Echos in GH Deficient Patients After Acromegaly Treatment
Clinical trial update on the effects of growth hormone on cardiac function, as measured by echocardiography, in growth hormone-deficient pat…
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CLINICAL_TRIALS trial_result · 2015-01-30Clinical Trial Update: Safety and Efficacy of Pasireotide Long Acting Release (LAR) vs. Octreotide LAR in Patients With Active Acromegaly [Phase 3]
Phase 3 trial comparing pasireotide long-acting release to octreotide long-acting release in active acromegaly completed with results posted…
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CLINICAL_TRIALS trial_result · 2015-01-21Clinical Trial Update: Efficacy and Safety of Pasireotide Long Acting Release (LAR) Versus Octreotide LAR or Lanreotide Autogel (ATG) in Patients With Inadequately Controlled Acromegaly [Phase 3]
A Phase 3 trial compares pasireotide long-acting release (LAR) with octreotide LAR or lanreotide Autogel in patients with inadequately contr…
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CLINICAL_TRIALS trial_result · 2014-12-05Clinical Trial Update: Calcium Homeostasis in Acromegaly: Effect of Surgical/Medical Treatment and Comparison With Nonfunctioning Pituitary Tumors
This completed clinical trial evaluated calcium homeostasis in acromegaly and how surgical or medical treatment affects it. It also compared…
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CLINICAL_TRIALS trial_result · 2014-10-28Clinical Trial Update: Fractionated Stereotactic Radiotherapy in Patients With Acromegaly
A completed clinical trial evaluating fractionated stereotactic radiotherapy for acromegaly.
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CLINICAL_TRIALS trial_result · 2014-09-16Clinical Trial Update: Glucose Tolerance in Acromegaly: The Influence of GH-excess on Glucose Metabolism and Insulin Resistance
A completed clinical trial examining how growth hormone excess in acromegaly influences glucose tolerance, insulin resistance, and glucose m…
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CLINICAL_TRIALS trial_result · 2014-07-31Clinical Trial Update: Somatostatin Analog Treatment of Acromegaly Before Pituitary Surgery : Comparison With Neurosurgery Alone [NA]
A completed trial evaluated preoperative somatostatin analogue therapy for acromegaly and compared it with neurosurgery alone before pituita…
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CLINICAL_TRIALS trial_result · 2014-06-02Clinical Trial Update: Preoperative Octreotide Treatment of Acromegaly [Phase 4]
This update notes the completion of a Phase 4 clinical trial evaluating preoperative octreotide treatment in patients with acromegaly.
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CLINICAL_TRIALS trial_result · 2013-12-23Clinical Trial Update: Lanreotide as Primary Treatment for Acromegalic Patients With Pituitary Gland Macroadenoma [Phase 3]
Phase 3 trial evaluating lanreotide as the primary treatment for acromegaly due to pituitary macroadenoma.