Acquired Immunodeficiency Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2011-04-25Clinical Trial Update: Rollover Study for Zerit (Stavudine) ER Studies (-096, -099) [Phase 3]
Phase 3 rollover studies of Zerit (stavudine) extended-release formulations have completed, reporting results in HIV infection and AIDS.
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CLINICAL_TRIALS trial_result · 2011-04-22Clinical Trial Update: DART I - A Phase IV Study of 3 Antiretroviral Medicines in Combination, in HIV Patients Who Have Not Been Previously Treated With Antiretroviral Therapy [NA]
DART I is a Phase IV trial evaluating a triple-antiretroviral drug combination in HIV patients who have not previously received antiretrovir…
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CLINICAL_TRIALS trial_result · 2011-03-29Clinical Trial Update: Pharmacokinetics of Lopinavir/Ritonavir at Three Different Doses. [Phase 1]
Phase 1 pharmacokinetics study evaluating the lopinavir/ritonavir combination at three different doses in individuals with Acquired immunode…
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CLINICAL_TRIALS trial_result · 2011-03-15Clinical Trial Update: Optimal Time to Initiate Antiretroviral Therapy in HIV & TB Coinfected Adults Being Treated for Tuberculosis [NA]
This clinical trial update discusses the optimal timing to initiate antiretroviral therapy in adults co-infected with HIV and tuberculosis w…
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CLINICAL_TRIALS trial_result · 2011-03-14Clinical Trial Update: An Efficacy Study of 2',3'-Dideoxyinosine (ddI) (BMY-40900) Administered Orally Twice Daily to Zidovudine Intolerant Patients With AIDS or AIDS-Related Complex [Phase 2]
Phase 2 efficacy study evaluating oral didanosine (ddI) in zidovudine-intolerant patients with AIDS or AIDS-related complex; the trial has c…
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CLINICAL_TRIALS trial_result · 2011-03-14Clinical Trial Update: Dideoxycytidine ( Ro 24-2027 ) A Randomized, Open-Label, Comparative Study of Dideoxycytidine ( ddC ) Versus Zidovudine ( AZT ) in Patients With AIDS or Advanced ARC Who Have Received Long-Term AZT Therapy. [Phase 2]
A Phase 2 randomized, open-label study comparing dideoxycytidine (zalcitabine, ddC) to zidovudine (AZT) in patients with AIDS or advanced HI…
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CLINICAL_TRIALS trial_result · 2011-03-14Clinical Trial Update: A Study of Azidothymidine Plus Methadone in Patients With AIDS and AIDS Related Complex (ARC) [NA]
Completed clinical trial evaluating azidothymidine (AZT) plus methadone in patients with AIDS and AIDS-related complex (ARC) who have HIV in…
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CLINICAL_TRIALS trial_result · 2011-03-07Clinical Trial Update: A Clinical Trial Comparing the Tolerability of Etravirine to Efavirenz in Combination With 2 Nucleoside/Nucleotide Reverse Transcriptase Inhibitors in Treatment-naive HIV-1 Infected Patients [Phase 2]
A Phase 2 study comparing tolerability of etravirine to efavirenz, each with two nucleoside/nucleotide reverse transcriptase inhibitors, in …
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CLINICAL_TRIALS trial_result · 2011-02-25Clinical Trial Update: Safety of Cotrimoxazole in HIV- and HAART-exposed Infants [Phase 4]
Phase 4 safety evaluation of cotrimoxazole (sulfamethoxazole-trimethoprim) in HIV- and HAART-exposed newborns has completed, noting safety e…
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CLINICAL_TRIALS trial_result · 2010-12-17Clinical Trial Update: VX-950-TiDP24-C134: Drug-drug Interaction Trial Between Combination of Efavirenz and Tenofovir Disoproxil Fumarate and Different Dosages of Telaprevir on Healthy Volunteer [Phase 1]
Phase 1 drug-drug interaction study assessing effects of combining efavirenz and tenofovir disoproxil fumarate with different doses of telap…
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EMA guidance · 2010-11-30World AIDS Day: 1 December 2010
EMA observes World AIDS Day (1 December 2010) and highlights ongoing efforts in HIV treatment, prevention, and innovation.
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CLINICAL_TRIALS trial_result · 2010-07-22Clinical Trial Update: Physiologic Growth Hormone Effects in HIV Lipodystrophy [NA]
This clinical trial update reports results on physiologic growth hormone effects in HIV lipodystrophy. The study has completed and results w…
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CLINICAL_TRIALS trial_result · 2010-07-21Clinical Trial Update: HIV/AIDS Kaposis Sarcoma: Comparison of Response to HAART vs HAART Plus CXT [Phase 4]
Phase 4 trial evaluating whether adding chemotherapy to HAART improves response in HIV infection and AIDS-related Kaposi's sarcoma; the stud…
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FDA approval · 2010-06-14FDA Approved: ZIDOVUDINE — Supplemental Application (Aurobindo Pharma Limited)
FDA approved a supplemental application for Zidovudine from Aurobindo Pharma Limited.
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CLINICAL_TRIALS trial_result · 2010-06-07Clinical Trial Update: The CORE Buprenorphine Project - An HIV Primary Care Program Demonstration
Update on a completed clinical trial of the CORE Buprenorphine Project, a HIV primary care program using buprenorphine. The study included p…
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CLINICAL_TRIALS trial_result · 2010-04-28Clinical Trial Update: TMC278-TiDP6-C130: Pharmacokinetics, Safety and Tolerability of TMC278 in Subjects With Mildly or Moderately Impaired Hepatic Function. [Phase 1]
Phase 1 PK and safety study assessing rilpivirine (TMC278) in HIV patients with mild-to-moderate hepatic impairment; focuses on pharmacokine…
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CLINICAL_TRIALS trial_result · 2010-04-12Clinical Trial Update: Safety and Efficacy of an Investigational Drug in Human Immunodeficiency Virus (HIV)-Infected Patients Failing Current Antiretroviral Therapies (0518-005)(COMPLETED) [Phase 2]
Phase 2 trial assessing safety and efficacy of an investigational HIV drug in patients failing current antiretroviral therapy, with results …
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CLINICAL_TRIALS trial_result · 2010-03-29Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of an Investigational Drug in HIV Infected Patients (0518-004)(COMPLETED) [Phase 2]
The document reports the completed Phase 2 study assessing the safety and efficacy of an investigational drug in HIV-infected patients, with…
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CLINICAL_TRIALS trial_result · 2010-02-26Clinical Trial Update: Treatment Simplification by Darunavir/Ritonavir 800/100 mg Once a Day Versus a Triple Combination Therapy With Darunavir/Ritonavir [Phase 3]
A Phase 3 trial compared once-daily darunavir/ritonavir 800/100 mg with a triple combination darunavir/ritonavir regimen in HIV infection; r…
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FDA approval · 2009-11-06FDA Approved: RETROVIR — Supplemental Application (ViiV Healthcare Company)
FDA approved a supplemental application for RETROVIR (Zidovudine) by ViiV Healthcare Company.
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CLINICAL_TRIALS research · 2009-10-29Clinical Trial Update: Research on Effect of Traditional Chinese Medicine (TCM) on Immune Reconstitution of HIV/AIDS Patients After Highly Active Antiretroviral Therapy (HAART) [NA]
This entry summarizes a clinical trial investigating the effect of traditional Chinese medicine on immune reconstitution in HIV/AIDS patient…
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CLINICAL_TRIALS research · 2009-10-29Clinical Trial Update: The Effect of Combination of Traditional Chinese Medicine (TCM) and Highly Active Antiretroviral Therapy (HAART) on Immune Reconstitution of HIV/AIDS Patients [NA]
This trial investigates whether combining traditional Chinese medicine with HAART affects immune reconstitution in HIV/AIDS patients.
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CLINICAL_TRIALS research · 2009-10-29Clinical Trial Update: Clinical Trials on the Effect of Immunity 1 (Fuzheng 1) on Immune Reconstitution of HIV Patients [NA]
This document describes a clinical trial evaluating Immunity 1 (Fuzheng 1) for immune reconstitution in HIV/AIDS patients; the current trial…
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CLINICAL_TRIALS trial_result · 2009-09-29Clinical Trial Update: Anatomic and Visual Function Assessments on Asymptomatic HIV-positive Patients
This clinical trial update notes the completion of a study assessing anatomic and visual function in asymptomatic HIV-positive patients.
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CLINICAL_TRIALS trial_result · 2009-09-29Clinical Trial Update: CD4 Cell Recovery in HIV-1 Patients Comparing 2 Treatment Regimes [Phase 3]
A phase 3 clinical trial update comparing two treatment regimens for HIV-1 treatment, focusing on CD4 cell recovery; the study status is com…