Acne Vulgaris
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-03-11Clinical Trial Update: Serum CXCL10 and CRP Levels in Patients With Acne Vulgaris in Correlation With Disease Severity
This clinical trial investigates serum CXCL10 and CRP levels in acne vulgaris patients and how these biomarkers relate to disease severity.
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FDA approval · 2025-03-10FDA Approved: TAZAROTENE — Supplemental Application (Mayne Pharma)
The FDA approved a supplemental application for tazarotene submitted by Mayne Pharma, extending its approved use.
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CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: Low Level Laser Versus Polarized Light in the Treatment of Acne Vulgaris [NA]
A completed clinical trial compared low level laser therapy with polarized light for the treatment of acne vulgaris. The study was sponsored…
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CLINICAL_TRIALS trial_result · 2025-03-04Clinical Trial Update: Correlation Between Depression Scores and Serum NF-ĸB/NLRP3 Axis, Biotinidase, and HMGB After Treatment With Isotretinoin in Patients With Acne Vulgaris [Phase 3]
Phase 3 trial update of isotretinoin for acne vulgaris, reporting on correlations between depression scores and serum NF-κB/NLRP3 axis, biot…
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CLINICAL_TRIALS trial_result · 2025-03-04Clinical Trial Update: A Study to Evaluate the Impact of Clascoterone 1% Cream on Skin Barrier Properties in Acne Prone Patients [Phase 4]
Phase 4 trial evaluating the impact of clascoterone 1% cream on skin barrier properties in acne-prone patients has completed with results po…
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FDA approval · 2025-03-03FDA Approved: TRETINOIN — Original Application (Encube Ethicals, Inc.)
The FDA approved Encube Ethicals’ original application for tretinoin, granting a generic version of the dermatology retinoid. This marks a f…
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FDA approval · 2025-02-27FDA Approved: TRETINOIN — Original Application (Aurobindo Pharma Limited)
FDA approved the original application for a generic tretinoin product from Aurobindo Pharma Limited.
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CLINICAL_TRIALS trial_result · 2025-02-20Clinical Trial Update: Reduced Side-Effects of Photodynamic Therapy for the Treatment of Moderate to Severe Acne (i-PDT) [Phase 1]
A Phase 1 clinical trial reports reduced side-effects for photodynamic therapy using i-PDT in treating moderate to severe acne vulgaris.
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CLINICAL_TRIALS trial_result · 2025-02-12Clinical Trial Update: Clinical Efficacy of the Product in the Management of Facial Post Inflammatory Hyperpigmentation (PIHP) Subjects
This clinical trial update reports the efficacy of a Cosmetique Active product for managing facial post-inflammatory hyperpigmentation, incl…
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CLINICAL_TRIALS research · 2025-01-31Clinical Trial Update: Effect of Multiple Subcisions on Rolling Acne Scars [NA]
Clinical trial update on the effect of multiple subcision procedures for rolling acne scars; the study is currently active but not recruitin…
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FDA approval · 2025-01-29FDA Approved: TRETINOIN — Supplemental Application (Glenmark Pharmaceuticals Inc., USA)
FDA approves Glenmark's supplemental application for tretinoin (all-trans retinoic acid), updating the product's regulatory status per the s…
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CLINICAL_TRIALS trial_result · 2025-01-28Clinical Trial Update: Pharmacokinetics, Safety and Tolerability of Clascoterone Cream 1% in Healthy Chinese Adult Subjects [Phase 1]
Phase 1 study evaluating pharmacokinetics, safety and tolerability of clascoterone 1% cream in healthy Chinese adults; study completed.
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CLINICAL_TRIALS trial_result · 2025-01-23Clinical Trial Update: To Compare the Efficacy of Intralesional Saline Versus 35% Trichloracetic Acid (TCA) Peel in the Treatment of Atrophic Acne Scars [Phase 2]
A Phase 2 trial comparing intralesional saline to a 35% Trichloroacetic acid peel for treating atrophic acne scars has completed.
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CLINICAL_TRIALS trial_result · 2025-01-16Clinical Trial Update: The Effectiveness and Safety of Cleanser Containing Triethyl Citrate, Pyruvic Acid, Combination Cream Containing Triethyl Citrate, Ethyl Linoleate, GT Peptide-10, Salicylic Acid 0,5%, Zinc Lactate, Hyaluronic Acid and Spot Cream Containing Triethyl Citrate, Ethyl Linoleate, GT Peptide-10, Honokiol [Phase 3]
Phase 3 clinical trial update evaluating the effectiveness and safety of three topical products for acne vulgaris (cleanser, combination cre…
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CLINICAL_TRIALS research · 2025-01-16Clinical Trial Update: Laser Treatment of Moderate to Severe Acne Vulgaris [NA]
An ongoing clinical trial at Massachusetts General Hospital is evaluating laser therapy for moderate to severe acne vulgaris and is currentl…
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CLINICAL_TRIALS trial_result · 2025-01-15Clinical Trial Update: Acne Detection Software (AcneDect)
A clinical trial evaluating AcneDect acne-detection software sponsored by University Hospital Basel has been terminated.
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CLINICAL_TRIALS trial_result · 2025-01-13Clinical Trial Update: Efficacy of La Roche Posay Routine in the Management of Facial Post Inflammatory Hyperpigmentation (PIHP)
Completed clinical trial evaluating the efficacy of the La Roche-Posay skincare routine for facial postinflammatory hyperpigmentation. Acne …
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FDA approval · 2025-01-13FDA Approved: TRETINOIN — Original Application (Aurobindo Pharma Limited)
FDA approved an Original Application for tretinoin from Aurobindo Pharma Limited, making a generic version of tretinoin available. This is a…
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CLINICAL_TRIALS trial_result · 2025-01-08Clinical Trial Update: Clinical Investigation on the Safety and Clinical Performance of Papix Acne Scar. [NA]
A completed clinical investigation assessing the safety and clinical performance of Papix Acne Scar; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-12-18Clinical Trial Update: The Effects of Oral Probiotics and Herbal Supplementation on the Gut Microbiome and Sebum Excretion Rate in Non-Cystic Acne [NA]
This clinical trial evaluated whether an oral probiotic and herbal supplement regimen affects the gut microbiome and sebum excretion rate in…
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: A Study Comparing Trifarotene Cream 0.005% to AKLIEF® CREAM (US REFERENCE LISTED DRUG), AKLIEF™ CREAM (CANADIAN REFERENCE PRODUCT) in the Treatment of Acne Vulgaris [Phase 1]
This document notes the completion of a Phase 1 trial comparing Trifarotene Cream 0.005% with AKLIEF Cream (US reference listed drug) and th…
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CLINICAL_TRIALS trial_result · 2024-12-09Clinical Trial Update: Effect of Systemic Isotretinoin on Serum Irisin Level in Acne Vulgaris Patients [NA]
This completed clinical trial evaluated whether systemic isotretinoin affects serum irisin levels in patients with acne vulgaris.
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CLINICAL_TRIALS trial_result · 2024-12-06Clinical Trial Update: Teledermatology vs. Face-to-Face Visits in the Follow-Up of Patients With Acne [NA]
A completed clinical trial compared teledermatology follow-up visits with traditional face-to-face visits for patients with acne vulgaris.
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FDA approval · 2024-12-04FDA Approved: DOXYCYCLINE — Original Application (Amneal Pharmaceuticals LLC)
FDA approved Amneal Pharmaceuticals LLC's generic doxycycline as an original ANDA product.
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: A Study Comparing Clindamycin Phosphate, Adapalene, and Benzoyl Peroxide Topical Gel 0.15%;3.1%;1.2% (Taro Pharmaceuticals U.S.A., Inc.) and CABTREO Topical Gel for the Treatment of Acne Vulgaris. [Phase 1]
Phase 1 trial comparing a triple-combination topical gel (clindamycin phosphate, adapalene, benzoyl peroxide) with CABTREO Topical Gel for a…